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1622869-09-3

C21H15F3N2O2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1622869-09-3 Structure

  • Basic information

    1. Product Name: C21H15F3N2O2
    2. Synonyms: C21H15F3N2O2
    3. CAS NO:1622869-09-3
    4. Molecular Formula:
    5. Molecular Weight: 384.358
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1622869-09-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C21H15F3N2O2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C21H15F3N2O2(1622869-09-3)
    11. EPA Substance Registry System: C21H15F3N2O2(1622869-09-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1622869-09-3(Hazardous Substances Data)

1622869-09-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1622869-09-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,2,8,6 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1622869-09:
(9*1)+(8*6)+(7*2)+(6*2)+(5*8)+(4*6)+(3*9)+(2*0)+(1*9)=183
183 % 10 = 3
So 1622869-09-3 is a valid CAS Registry Number.

1622869-09-3Downstream Products

1622869-09-3Relevant articles and documents

Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold

Flaherty, Daniel P.,Simpson, Denise S.,Miller, Melissa,Maki, Brooks E.,Zou, Beiyan,Shi, Jie,Wu, Meng,McManus, Owen B.,Aubé, Jeffrey,Li, Min,Golden, Jennifer E.

, p. 3968 - 3973 (2014/09/03)

TASK-1 is a two-pore domain potassium channel that is important to modulating cell excitability, most notably in the context of neuronal pathways. In order to leverage TASK-1 for therapeutic benefit, its physiological role needs better characterization; however, designing selective inhibitors that avoid the closely related TASK-3 channel has been challenging. In this study, a series of bis-amide derived compounds were found to demonstrate improved TASK-1 selectivity over TASK-3 compared to reported inhibitors. Optimization of a marginally selective hit led to analog 35 which displays a TASK-1 IC 50 = 16 nM with 62-fold selectivity over TASK-3 in an orthogonal electrophysiology assay.

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