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1623023-29-9

ethyl 6-methyl-1-(4-methylbenzyl)-1,4-dihydrothieno[2',3'-4,5]cyclopenta[1,2c]pyrazole-3-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1623023-29-9 Structure

  • Basic information

    1. Product Name: ethyl 6-methyl-1-(4-methylbenzyl)-1,4-dihydrothieno[2',3'-4,5]cyclopenta[1,2c]pyrazole-3-carboxylate
    2. Synonyms: ethyl 6-methyl-1-(4-methylbenzyl)-1,4-dihydrothieno[2',3'-4,5]cyclopenta[1,2c]pyrazole-3-carboxylate
    3. CAS NO:1623023-29-9
    4. Molecular Formula:
    5. Molecular Weight: 352.457
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1623023-29-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl 6-methyl-1-(4-methylbenzyl)-1,4-dihydrothieno[2',3'-4,5]cyclopenta[1,2c]pyrazole-3-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl 6-methyl-1-(4-methylbenzyl)-1,4-dihydrothieno[2',3'-4,5]cyclopenta[1,2c]pyrazole-3-carboxylate(1623023-29-9)
    11. EPA Substance Registry System: ethyl 6-methyl-1-(4-methylbenzyl)-1,4-dihydrothieno[2',3'-4,5]cyclopenta[1,2c]pyrazole-3-carboxylate(1623023-29-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1623023-29-9(Hazardous Substances Data)

1623023-29-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1623023-29-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,3,0,2 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1623023-29:
(9*1)+(8*6)+(7*2)+(6*3)+(5*0)+(4*2)+(3*3)+(2*2)+(1*9)=119
119 % 10 = 9
So 1623023-29-9 is a valid CAS Registry Number.

1623023-29-9Relevant articles and documents

Tricyclic pyrazoles part 7. Discovery of potent and selective dihydrothienocyclopentapyrazole derived CB2 ligands

Pinna, Giansalvo,Curzu, Maria Michela,Dore, Antonio,Lazzari, Paolo,Ruiu, Stefania,Pau, Amedeo,Murineddu, Gabriele,Pinna, Gérard A.

, p. 747 - 757 (2014)

A series of dihydrothienocyclopentapyrazole-based derivatives was synthesized and evaluated for the affinity at CB1 and CB2 receptors. The major term, the 6-methyl-1-(1,4-dichlorophenyl)-N-piperidinyl)-1,4- dihydrothieno[2′,3′-4,5]cyclopenta[1,2-c]pyrazole-3-carboxamide (6a), displayed a high affinity and good selectivity for CB2 receptors (Ki values of 2.30 nM for CB2 receptor and 440 nM for CB1 receptors respectively). Subsequent analogue preparation resulted in the identification of compounds such as 6b, 6d, 6e, 6k, 6l, 6m, 6s and 6t that showed 1.3-485 fold selectivity for CB2 receptors with potencies in the 1.1-7.2 nM range. These compounds profiled as full agonists at CB2 receptor in an inhibition assay of P-ERK 1/2 up regulation in HL-60 cells.

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