16231-77-9

Basic information

• Product Name: 2-CHLORO-N-(2-CYANOETHYL)-N-PHENYLACETAMIDE
• Synonyms: AKOS BBS-00006355;2-CHLORO-N-(2-CYANOETHYL)-N-PHENYLACETAMIDE;OTAVA-BB BB7020410107
• CAS NO: 16231-77-9
• Molecular Formula: C₁₁H₁₁ClN₂O
• Molecular Weight: 222.67
• Mol File: 16231-77-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 67-69 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 378.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.245±0.06 g/cm3(Predicted)
• PKA: 0.06±0.50(Predicted)
• CAS DataBase Reference: 2-CHLORO-N-(2-CYANOETHYL)-N-PHENYLACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(2-CYANOETHYL)-N-PHENYLACETAMIDE(16231-77-9)
• EPA Substance Registry System: 2-CHLORO-N-(2-CYANOETHYL)-N-PHENYLACETAMIDE(16231-77-9)

Safety Data

• Hazardous Substances Data: 16231-77-9(Hazardous Substances Data)

Upstream product

• 1075-76-9 N-cyanoethylaniline 
• 79-04-9 chloroacetyl chloride 

Relevant articles and documents

Synthesis of New Substituted 1-(3-Pyridyl)pyridinium Salts and 3,4-Diamino-2(1H)-pyridinones

2-acrylonitriles 1 and 3-propionitriles 4 were allowed to react with pyridine to form the 1-(4-amino-3-pyridyl)pyridinium salts 3 and 1-(4-amino-5,6-dihydro-3-pyridyl)pyridinium salts 6.Dehydrogenation of 6 with bromine in glacial acetic acid afforded 1-(4-amino-3-pyridyl)pyridinium bromides 7.Treatment of 3 and 7 with hydrazine hydrate yielded the 3,4-diamino-2(1H)-pyridinones 8.Ananlogously to the other ortho-diamines, the substituted thiadiazolopyridin-4-one 10, selenadiazolopyridin-4-one 11, and further derivatives were obtained from 8.N-(Chloroacetyl) derivatives of acetylacetoneimide 13 and 3-oxo-3-phenyl-2-(phenylhydrazono)propionamide 17 were treated with pyridine to give 1-(3-pyridinyl)pyridinium salts 14 and 18, respectively. - Key Words: Pyridines