162332-13-0Relevant articles and documents
Cytotoxic effects of C-glycosides in HOS and HeLa cell lines
Sanhueza, Carlos A.,Mayato, Carlos,Machin, Ruben P.,Padron, Jose M.,Dorta, Rosa L.,Vazquez, Jesus T.
, p. 3676 - 3681 (2008/02/05)
Fifty-two C-glycosides were synthesized and their in-vitro antiproliferative activity screened against human cervical carcinoma (HeLa) and osteosarcoma (HOS) cell lines. Nine of them had growth inhibitions (GI50 values) below 10 μM, the C-gluco
A new procedure for highly regio- and stereoselective iodoacetoxylation of protected glycals and α-1,2-cyclopropanated sugars
Gammon, David W.,Kinfe, Henok H.,De Vos, Dirk E.,Jacobs, Pierre A.,Sels, Bert F.
, p. 141 - 157 (2008/02/11)
Protected glycals and -1,2-cyclopropanated sugars were converted in high yields and selectivities in less than 2h at low temperatures to 2-deoxy-2-iodoglycosyl acetates or novel 2-deoxy-2-iodomethylglycosyl acetates using the simple, inexpensive reagent m
Studies towards the synthesis of the C29-C51 fragment of altohyrtin A
Fernandez-Megia, Eduardo,Gourlaouen, Nelly,Ley, Steven V.,Rowlands, Gareth J.
, p. 991 - 994 (2007/10/03)
The synthesis of the highly substituted E and F pyran fragment 23 of altohyrtin A 1 from tri-O-benzyl-D-glucal 5 is described. The synthesis of a model compound 31 containing the altohyrtin A triene side-chain outlines the proposed strategy for the elabor
Synthesis and Reactions of 1,2-Cyclopropanated Sugars
Ramana,Murali,Nagarajan
, p. 7694 - 7703 (2007/10/03)
Diastereospecific cyclopropanation of glycals 1, 2, 3, 4, and 41 was carried out using either dihalocarbene addition or zinc-carbenoid addition to yield 1,2-cyclopropanated sugars. Dichloroand dibromocarbenes added stereoselectively anti to the C3/s
Synthesis of 1,2-Cyclopropanated Sugars from Glycals
Murali, R.,Ramana, C. V.,Nagarajan, M.
, p. 217 - 218 (2007/10/02)
Syntheses of both forms of cyclopropanated sugars from glycals by (i) Simmons-Smith reaction and (ii) dichlorocarbene addition followed by dehalogenation are described.