162357-99-5

Upstream product

• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 122-97-4 3-Phenyl-1-propanol 
• 637-59-2 1-Bromo-3-phenylpropane 
• 53712-77-9 1-bromo-3-(4-nitrophenyl)propane 
• 1258945-86-6 tert-butyl N-[1-(4-nitrophenyl)-3-oxopropan-2-yl]carbamate 

Downstream Products

• 1142811-85-5 2-Amino-5-(4-nitrophenyl)-pentan-1-ol 
• 1206716-20-2 2-amino-5-(4-nitrophenyl)pentanoic acid 
• 1174340-04-5 2-amino-5-(4-nitrophenyl)pentanoic acid methyl ester 
• 1142811-83-3 {tert-butoxycarbonylmethyl-[1-hydroxymethyl-4-(4-nitrophenyl)butyl]amino}acetic acid tert-butyl ester 
• 855650-54-3 acetylamino-[3-(4-amino-phenyl)-propyl]-malonic acid diethyl ester 

Relevant academic research and scientific papers

Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using

Substituted 1,4,7-triazacyclononane-N,N′,N″-triacetic acid and 1,4,7,10-tetraazacyclcododecane-N,N′,N″,N′″-tetraacetic acid compounds with a pendant amino or hydroxyl group, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders.

A highly effective bifunctional ligand for radioimmunotherapy applications

A novel bifunctional ligand (3p-C-NETA) for antibody-targeted radioimmunotherapy (RIT) of β-emitting radioisotopes 90Y and 177Lu was efficiently synthesized via an unexpected regiospecific ring opening of an aziridinium ion. 3p-C-NET

Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using

Substituted 1,4,7-triazacyclononane-N,N′,N″-triacetic acid and 1,4,7,10-tetraazacyclcododecane-N,N′,N″,N′″-tetraacetic acid compounds with a pendant amino or hydroxyl group, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders.

2-amino-1,3-propanediol compound and immunosuppressant

2-Amino-1,3-propanediol compounds of the formula (I) STR1 wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R2, R3, R4 and R5 are the same or different and each is a hydrogen, an alkyl, an aralkyl, an acyl or an alkoxycarbonyl, pharmaceutically acceptable salts thereof and immunosuppressants comprising these compounds as active ingredients. The 2-amino-1,3-propanediol compounds of the present invention show immunosuppressive action and are useful for suppressing rejection in organ or bone marrow tranplantation, prevention and treatment of autoimmune diseases or as reagents for use in medicinal and pharmaceutical fields.