1142811-83-3

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 1142811-85-5 2-Amino-5-(4-nitrophenyl)-pentan-1-ol 
• 162357-99-5 2-acetylamino-2-[3-(4-nitrophenyl)propyl]malonic acid diethyl ester 
• 122-97-4 3-Phenyl-1-propanol 
• 637-59-2 1-Bromo-3-phenylpropane 
• 53712-77-9 1-bromo-3-(4-nitrophenyl)propane 
• 1206716-20-2 2-amino-5-(4-nitrophenyl)pentanoic acid 
• 1174340-04-5 2-amino-5-(4-nitrophenyl)pentanoic acid methyl ester 

Downstream Products

• 1142811-90-2 1,1-bis[2-(tert-butoxy)-2-oxoethyl]-2-[3-(4-nitrophenyl)propyl]aziridin-1-ium bromide 
• 1258945-71-9 di-tert-butyl 2,2'-(2-bromo-5-(4-nitrophenyl)pentylazanediyl)diacetate 
• 1392222-51-3 {4-[5-(4-amino-phenyl)-2-bis(carboxymethyl)aminopentyl]-7-carboxymethyl-[1,4,7]triazo-nan-1-yl}acetic acid 
• 1392222-50-2 C₄₁H₇₁N₅O₈ 
• 1258945-99-1 tert-butyl-2-[(1-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-1,4,7-triazonan-1-yl}-5-[4-(hydroxyl-nitro)phenyl]-pentan-2-yl)[2-(tert-butoxy)-2-oxoethyl]amino]acetate 
• 1258946-46-1 tert-butyl 2-[(1-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-1,4,7-triazonan-1-yl}-5-[4-nitrophenyl]pentan-2-yl)[2-(tert-butoxy)-2-oxoethyl]amino]acetate 
• 1392222-48-8 tert-butyl 2-{[2-(tert-butoxy)-2-oxoethyl][2-iodo-5-(4-nitrophenyl)pentyl]amino}acetate 
• 1392222-52-4 {4-[2-(bis-carboxymethylamino)-5-(4-isothiocyanatophenyl) pentyl]-7-carboxymethyl-[1,4,7]triazonan-1-yl}acetic acid 

Relevant academic research and scientific papers

Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using

Substituted 1,4,7-triazacyclononane-N,N′,N″-triacetic acid and 1,4,7,10-tetraazacyclcododecane-N,N′,N″,N′″-tetraacetic acid compounds with a pendant amino or hydroxyl group, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders.

A highly effective bifunctional ligand for radioimmunotherapy applications

A novel bifunctional ligand (3p-C-NETA) for antibody-targeted radioimmunotherapy (RIT) of β-emitting radioisotopes 90Y and 177Lu was efficiently synthesized via an unexpected regiospecific ring opening of an aziridinium ion. 3p-C-NET

Bimodal ligands with macrocyclic and acyclic binding moieties, complexes and compositions thereof, and methods of using

Substituted 1,4,7-triazacyclononane-N,N′,N″-triacetic acid and 1,4,7,10-tetraazacyclcododecane-N,N′,N″,N′″-tetraacetic acid compounds with a pendant amino or hydroxyl group, metal complexes thereof, compositions thereof, and methods of making and use in diagnostic imaging and treatment of cellular disorders.

Stable aziridinium salts as versatile intermediates: Isolation and regio- and stereoselective ring-opening and rearrangement

Rock trapping and exploration: Aziridinium bromide salts were discovered serendipitously during bromination of N,N-dicarboxymethylated β-amino alcohols. Regiospecific ring-opening and rearrangement of the isolated, surprisingly stable aziridinium salts produces useful molecules including C-functionalized oxomorpholines and α,β-unsaturated amines. 2009 Wiley-VCH Verleg GmbH & Co. KGaA, Weinheim.