16236-51-4

Upstream product

• 103-80-0 phenylacetyl chloride 
• 108-90-7 chlorobenzene 
• 563-41-7 semicarbazide hydrochloride 
• 1889-71-0 4'-chloro-2-phenylacetophenone 

Downstream Products

• 877224-42-5 4-(4-chloro-phenyl)-5-phenyl-[1,2,3]thiadiazole 

Relevant academic research and scientific papers

Syntheses of 4,5-diaryl-1,2,3-thiadiazoles

Reaction of thionyl chloride with semicarbazones of 1-(4- methylsulfonylphenyl)-2-(4-substituted pheny)lethanone gave 4-(4- methylsulfonylphenyl)-5-(4-substituted) pheny-1,2,3-thiadiazoles 5. Compounds 5-phenyl-4-(substitutedphenyl)-1,2,3-thiadiazoles 14 were similarly prepared. Chlorosulfonation of the latter followed by ammonia gave the desired compounds 5-(4-aminosulfonylphenyl)-4-(substituted) phenyl-1,2,3-thiadiazoles 6. Copyright Taylor & Francis Inc.