1623747-31-8Relevant articles and documents
Gold(I) N-heterocyclic carbene complexes with naphthalimide ligands as combined thioredoxin reductase inhibitors and DNA intercalators
Meyer, Andreas,Oehninger, Luciano,Geldmacher, Yvonne,Alborzinia, Hamed,W?lfl, Stefan,Sheldrick, William S.,Ott, Ingo
, p. 1794 - 1800 (2014)
Organometallic conjugates consisting of a gold(I) N-heterocyclic carbene (NHC) moiety and a naphthalimide were prepared and investigated as cytotoxic agents that interact with both DNA and the disulfide reductase enzyme thioredoxin reductase (TrxR). The c