1623809-05-1

Basic information

• Product Name: C₁₈H₂₀N₂O₂S
• Synonyms: C₁₈H₂₀N₂O₂S
• CAS NO: 1623809-05-1
• Molecular Weight: 328.435
• Mol File: 1623809-05-1.mol

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₀N₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₀N₂O₂S(1623809-05-1)
• EPA Substance Registry System: C₁₈H₂₀N₂O₂S(1623809-05-1)

Safety Data

• Hazardous Substances Data: 1623809-05-1(Hazardous Substances Data)

Upstream product

• 130649-66-0 1-(4-Methylphenyl)-3-buten-1-one 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Downstream Products

• 1623809-18-6 C₁₈H₁₉BrN₂O₂S 
• 90861-52-2 1H-2-amino-4-toluoylpyrazole 

Relevant articles and documents

Palladium-Catalyzed Ring-Forming Alkene Aminoaroylation of Unsaturated Hydrazones and Sulfonamides

The first example of a Pd(OAc)2-catalyzed ring-forming alkene aminoaroylation of unsaturated hydrazones and sulfonamides is described. This protocol features the use of diaryliodonium salts as both oxidants and aryl sources, thus enabling mild

Organophotocatalytic Generation of N- and O-Centred Radicals Enables Aerobic Oxyamination and Dioxygenation of Alkenes

A cooperative TEMPO and photoredox catalytic strategy was applied for the first time to the direct conversion of N?H and O?H bonds into N- and O-centred radicals, enabling a general and selective oxidative radical oxyamination and dioxygenation of various

A visible-light photocatalytic N-radical cascade of hydrazones for the synthesis of dihydropyrazole-fused benzosultams

An efficient visible light photocatalytic and external oxidant-free N-radical 5-exo cyclization/addition/aromatization cascade of β,γ-unsaturated hydrazones is described, which provides a practical route to various biologically interesting dihydropyrazole

PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

A PhI(OAc)2-promoted radical cyclization of β,γ-unsaturated hydrazones and oximes has been developed for an efficient synthesis of various valuable pyrazoline and isoxazoline derivatives with satisfactory yields (up to 96%) under mild condition

Photocatalytic Generation of N-Centered Hydrazonyl Radicals: A Strategy for Hydroamination of β,γ-Unsaturated Hydrazones

A visible-light photocatalytic generation of N-centered hydrazonyl radicals has been accomplished for the first time. This approach allows efficient intramolecular addition of hydrazonyl radical to terminal alkenes, thus providing hydroamination and oxyamination products in good yields. Importantly, the protocol involves deprotonation of an N-H bond and photocatalytic oxidation to an N-centered radical, thus obviating the need to prepare photolabile amine precursors or the stoichiometric use of oxidizing reagents.

Efficient synthesis of dihydropyrazoles by halocyclization of β,γ-unsaturated hydrazones

An efficient halocyclization of β,γ-unsaturated hydrazones with N-bromosuccinimide was developed without the addition of any additives under mild reaction conditions to provide facile access to biologically important 4,5-dihydropyrazoles. Under the optimized conditions, a variety of highly substituted 4,5-dihydropyrazole derivatives were obtained in generally good yields. Moreover, this reaction can be further applied to the synthesis of pyrazoles in a one-pot fashion. Copyright