130649-66-0Relevant articles and documents
Indium-mediated allylation of acyl cyanides in aqueous media: A convenient synthesis of β,γ-unsaturated ketones
Yoo, Byung Woo,Choi, Kwang Hyun,Lee, Sung Jae,Nam, Ghil Soo,Chang, Kwan Young,Kim, Sung Hoon,Kim, Joong Hyup
, p. 839 - 846 (2002)
The indium-mediated allylation reaction of acyl cyanides with allyl halides in aqueous media afforded a variety of β,γ-unsaturated ketones in moderate to good yields under mild and neutral conditions.
Microwave-assisted catalytic allylation of aldehydes promoted by a mesoporous silica-supported BINOL ligand in solid media
Liu, Guohua,Gao, Yan,Lu, Xiaoquan,Liu, Mouming,Zhang, Fang,Li, Hexing
, p. 3184 - 3186 (2008)
An efficient and operationally simple method for catalytic allylation has been developed and its application in the microwave-assisted catalytic allylation of aldehydes in solid media was investigated. The Royal Society of Chemistry.
Organocatalytic Asymmetric Synthesis of Cyclic Acetals with Spirooxindole Skeleton
Shikari, Amit,Mandal, Koushik,Chopra, Deepak,Pan, Subhas Chandra
, p. 58 - 63 (2021/11/09)
An organocatalytic asymmetric synthesis of cyclic acetal with spirooxindole skeleton has been developed via a domino reaction between isatin and γ-hydroxy enones. Bifunctional squaramide catalyst with adamantyl motif was found to be the most effective for the cascade reaction. With 10 mol% of the catalyst, the desired products were obtained in 1.8:1 to 9:1 diastereo- and 86% to >99% enantioselectivities from a range of substituted isatins and γ-hydroxy enones. (Figure presented.).
Copper-catalyzed radical oxyallylation of olefins for the construction of alkene-containing isoxazolines
He, Xiaoxue,Qian, Lijie,Dai, Yuyu,Yan, Xinhuan,Li, Xiaoqing,Xu, Xiangsheng
, (2021/05/31)
A radical-mediated approach to alkene oxyallylation using allylic oximes is described. The reaction proceeds under copper-catalytic redox-neutral conditions and tolerates various functional groups. This protocol thus enables the synthesis of structurally valuable isoxazolines and the introduction of a versatile olefin motif in a single step.
Electrochemical Chalcogenation of β,γ-Unsaturated Amides and Oximes to Corresponding Oxazolines and Isoxazolines
Baidya, Mrinmay,De Sarkar, Suman,Mahanty, Kingshuk,Maiti, Debabrata,Mallick, Samrat
, (2020/02/04)
The current report represents a transition-metal-free synthesis of oxazoline and isoxazoline derivatives by a tandem electro-oxidative chalcogenation-cyclization process. Both C?Se and C?S bond-forming protocols were developed without using any external oxidant and the reaction was performed at room temperature, open to the air. Using this methodology, 29 substituted oxazoline and 16 substituted isoxazoline derivatives were synthesized with up to 91% isolated yield. (Figure presented.).