1623809-22-2Relevant articles and documents
Efficient synthesis of dihydropyrazoles by halocyclization of β,γ-unsaturated hydrazones
Hu, Xiao-Qiang,Chen, Jia-Rong,Wei, Qiang,Liu, Feng-Lei,Deng, Qiao-Hui,Zou, You-Quan,Xiao, Wen-Jing
, p. 3082 - 3086 (2014/06/09)
An efficient halocyclization of β,γ-unsaturated hydrazones with N-bromosuccinimide was developed without the addition of any additives under mild reaction conditions to provide facile access to biologically important 4,5-dihydropyrazoles. Under the optimized conditions, a variety of highly substituted 4,5-dihydropyrazole derivatives were obtained in generally good yields. Moreover, this reaction can be further applied to the synthesis of pyrazoles in a one-pot fashion. Copyright