16241-31-9Relevant articles and documents
Tropolones as lead-like natural products: The development of potent and selective histone deacetylase inhibitors
Ononye, Sophia N.,Vanheyst, Michael D.,Oblak, E. Zachary,Zhou, Wangda,Ammar, Mohamed,Anderson, Amy C.,Wright, Dennis L.
supporting information, p. 757 - 761 (2013/09/02)
Natural products have long been recognized as a rich source of potent therapeutics but further development is often limited by high structural complexity and high molecular weight. In contrast, at the core of the thujaplicins is a lead-like tropolone scaf