162425-16-3

Upstream product

• 162272-49-3 (R)-Pantolactone (1R,6S)-1-cyano-6-phenyl-3-cyclohexene-1-carboxylate 
• 162425-07-2 (1R,2S)-1-Cyano-2-phenyl-1-cyclohexanecarboxylic acid 
• 162425-06-1 (1R,6S)-1-Cyano-6-phenyl-3-cyclohexene-1-carboxylic acid 
• 142635-87-8 (E)-2-cyanocinnamate of (R)-pantolactone 
• 165882-92-8 Methyl (1R,2S)-1-cyano-2-phenyl-1-cyclohexanecarboxylate 

Downstream Products

• 162425-17-4 Methyl (1S,2S)-1-isocyanato-2-phenyl-1-cyclohexanecarboxylate 

Relevant academic research and scientific papers

Asymmetric Diels-Alder Reactions of Chiral (E)-2-Cyanocinnamates. 2. Synthesis of the Four 1-Amino-2-phenyl-1-cyclohexanecarboxylic Acids in Enantiomerically Pure Form

High and complementary diastereoselectivities were obtained in the asymmetric Diels-Alder reactions of chiral (E)-2-cyanocinnamates with butadiene when (S)-ethyl lactate and (R)-pantolactone were used as chiral auxiliaries in the presence of TiCl4.The mos