1624315-01-0

Upstream product

• 1624315-16-7 rac-4-bromo[2.2]paracyclophan-13-ylenebis-(4-trifluoromethylphenyl)phosphine sulfide 
• 1624315-15-6 rac-4-bromo[2.2]paracyclophan-13-ylene-bis-(4-trifluoromethylphenyl)phosphine oxide 
• 1908-61-8 4-bromo[2.2]paracyclophane 
• 1624290-44-3 C₃₀H₂₃F₆OP 
• 13685-24-0 bis(4-trifluoromethylphenyl)phosphine chloride 
• 1624314-94-8 rac-4-di-p-trifluoromethylphenylphosphino-13-dicyclohexylphosphino[2.2]paracyclophane 
• 1624315-19-0 rac-4-bromo[2.2]paracyclophan-13-ylenebis-(4-trifluoromethylphenyl)phosphine 

Relevant academic research and scientific papers

Unsymmetrical bisphosphines for the amidation of aryl chlorides: A kinetic study

The rate-determining step of the palladium-catalyzed amidation of 4-chlorotoluene with benzamide in the presence of unsymmetrical bisphosphines was investigated. Isostructural [2.2]paracyclophane-derived bisphosphines bearing dicyclohexylphosphino and diarylphosphino moieties were investigated as ligands in the oxidative addition and reductive elimination by kinetic studies. The reductive elimination was accelerated when a bisphosphine ligand was applied that contained an electron-rich phosphine group and a less electron-releasing phosphino moiety. Apart from the reductive elimination, the transmetallation had the largest impact on the palladium-catalyzed amidation of aryl halides. Copyright