162473-76-9

Upstream product

• 162473-73-6 3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 
• 162473-75-8 (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester 
• 61-90-5 L-leucine 
• 13748-90-8 (S)-2-hydroxyl-3,3-dimethylbutyric acid 
• 17392-84-6 methyl (2S)-2-hydroxy-4-methylpentanoate 
• 65806-89-5 (R)-2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionic acid 
• 162473-72-5 (S)-2-(4-methoxybenzyloxy)-4-methylpentanoic acid 
• 162473-74-7 (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoyl chloride 
• 1026148-52-6 3-[(R)-2-Amino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 2-trimethylsilanyl-ethyl ester 
• 162472-69-7 3-[(R)-2-Benzyloxycarbonylamino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 2-trimethylsilanyl-ethyl ester 
• 162472-70-0 3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 2-trimethylsilanyl-ethyl ester 
• 167276-14-4 C₃₅H₅₀O₂Si₂ 
• 1026475-30-8 2,2-Dimethyl-propionic acid (2R,3S)-5-(tert-butyl-diphenyl-silanyloxy)-2-methyl-3-triethylsilanyloxy-pentyl ester 
• 167276-13-3 (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-pentane-1,3-diol 

Downstream Products

• 162600-54-6 arenastatin A 
• 162600-54-6 cryptophycin-24 
• 1027309-65-4 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-2-methyl-1-(2-oxo-ethyl)-4-phenyl-but-3-enyl ester 
• 162473-78-1 desepoxyarenastatin A 
• 162473-77-0 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-1-(2-hydroxy-ethyl)-2-methyl-4-phenyl-but-3-enyl ester 

Relevant academic research and scientific papers

A total synthesis of arenastatin A, an extremely potent cytotoxic depsipeptide, from the Okinawan marine sponge dysidea arenaria

An asymmetric synthesis of a cyclic depsipeptide arenastatin A (1), which was isolated from the marine sponge Dysidea arenaria and exhibited extremely potent cytotoxicity with IC50 5 pg/ml for KB cells, has been accomplished.