162473-75-8

Basic information

• Product Name: (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester
• Synonyms: (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester
• CAS NO: 162473-75-8
• Molecular Weight: 678.984
• Mol File: 162473-75-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester(162473-75-8)
• EPA Substance Registry System: (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester(162473-75-8)

Safety Data

• Hazardous Substances Data: 162473-75-8(Hazardous Substances Data)

Upstream product

• 167276-14-4 C₃₅H₅₀O₂Si₂ 
• 1026475-30-8 2,2-Dimethyl-propionic acid (2R,3S)-5-(tert-butyl-diphenyl-silanyloxy)-2-methyl-3-triethylsilanyloxy-pentyl ester 
• 1026222-43-4 2,2-Dimethyl-propionic acid (2R,3S)-5-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-2-methyl-pentyl ester 
• 162473-69-0 (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-3-triethylsilanyloxy-pentan-1-ol 
• 162473-68-9 methyl 5-(tert-butyldiphenylsilyl)oxy-2-pentenoate 
• 167276-13-3 (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-pentane-1,3-diol 
• 162473-71-4 (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid methyl ester 
• 162473-72-5 (S)-2-(4-methoxybenzyloxy)-4-methylpentanoic acid 
• 127047-71-6 3-(tert-butyldiphenylsilyloxy)propan-1-ol 
• 17392-84-6 methyl (2S)-2-hydroxy-4-methylpentanoate 
• 116003-84-0 (2S,3S)-(3-(2-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)ethyl)-2-oxiranyl)methan-1-ol 
• 127665-77-4 (E)-5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)pent-2-en-1-ol 
• 112897-03-7 3-(tert-butyldiphenylsilyloxy)-1-propanal 
• 13748-90-8 (S)-2-hydroxyl-3,3-dimethylbutyric acid 

Downstream Products

• 162600-54-6 arenastatin A 
• 162600-54-6 cryptophycin-24 
• 162473-77-0 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-1-(2-hydroxy-ethyl)-2-methyl-4-phenyl-but-3-enyl ester 
• 1027309-65-4 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-2-methyl-1-(2-oxo-ethyl)-4-phenyl-but-3-enyl ester 
• 172225-71-7 (S)-2-(3-tert-Butoxycarbonylamino-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-2-(4-methoxy-phenyl)-1-(2-trimethylsilanyl-ethoxycarbonyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester 
• 172225-78-4 (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-2-(4-methoxy-phenyl)-1-(2-trimethylsilanyl-ethoxycarbonyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester 
• 1026176-43-1 (S)-2-Hydroxy-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-2-(4-methoxy-phenyl)-1-(2-trimethylsilanyl-ethoxycarbonyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester 
• 1027174-40-8 (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-2-methyl-1-(2-oxo-ethyl)-4-phenyl-but-3-enyl ester 
• 162473-78-1 desepoxyarenastatin A 
• 1026075-66-0 (S)-2-(4-Methoxy-benzyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-(2-hydroxy-ethyl)-2-methyl-4-phenyl-but-3-enyl ester 
• 162473-76-9 (S)-2-{3-[(R)-2-[2-(Diethoxy-phosphoryl)-acetylamino]-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (E)-(1S,2R)-1-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-methyl-4-phenyl-but-3-enyl ester 

Relevant articles and documents

Improved total synthesis and structure-activity relationship of arenastatin A, a potent cytotoxic spongean depsipeptide

An efficient asymmetric synthesis of a cyclic depsipeptide arenastatin A (1) is described. 1, isolated from the marine sponge Dysidea arenaria, exhibited extremely potent cytotoxicity with IC50 of 5 pg/ml for KB cells, and in this context the s