162491-52-3

Upstream product

• 100-39-0 benzyl bromide 
• 162491-62-5 (2S,3R,4S)-2-(hydroxymethyl)-5-methoxyoxolane-3,4-diol 
• 162491-51-2 2-[(1S,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole 
• 16838-89-4 2,3,5-tri-O-benzyl-α-L-ribofuranose 
• 108-24-7 acetic anhydride 
• 162438-96-2 2-[(1S,2R,3S,4S)-2,3,5-tris(benzyloxy)-4-benzylsulfonyloxy-1-hydroxypent-1-yl]-N-triphenylmethylimidazole 
• 64363-77-5 methyl 2,3,5-tri-O-benzyl-D-ribofuranoside 
• 1824-96-0 methyl ribofuranoside 
• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 

Downstream Products

• 162491-53-4 (5R,6S,7S,8S)-6,7-bis(benzyloxy)-5-benzyloxymethyl-5,6,7,8-tetrahydro-8-hydroxyimidazo[1,2-a]pyridine 
• 162438-97-3 Benzoic acid (5R,6S,7S,8S)-6,7-bis-benzyloxy-5-benzyloxymethyl-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-8-yl ester 
• 169134-66-1 (5R,6S,7S,8S)-2-allyl-6,7-bis(benzyloxy)-5-benzyloxymethyl-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 
• 169134-64-9 (5R,6S,7S,8S)-6,7-bis(benzyloxy)-5-benzyloxymethyl-2,3-dibromo-8-(t-butyldimethylsilyloxy)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 
• 162438-95-1 (5R,6S,7S,8S)-8-azido-6,7-bis(benzyloxy)-5-benzyloxymethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

The total synthesis of a glycosidase inhibitor, nagstatin

A glycosidase inhibitor, nagstatin, has been synthesized from protected L-ribofuranose through the inter- and intramolecular nucleophilic reactions of the imidazole moieties and the regioselective introduction of a carboxymethyl group.

Total Syntheses of De-branched Nagstatin and Its Analogs Having Glycosidase Inhibiting Activities

De-branched nagstatin and its analogs have been synthesized from protected L-ribo- and xylo-furanoses through the inter- and intra-molecular nucleophilic reactions with the imidazole moieties.