162504-85-0

Basic information

• Product Name: 1-N-CBZ-PIPERIDIN-4-YLOXY)ACETIC ACID
• Synonyms: 2-(1-CBZ-PIPERIDIN-4-YLOXY)-ACETIC ACID;2-((1-((Benzyloxy)carbonyl)piperidin-4-yl)oxy)acetic acid
• CAS NO: 162504-85-0
• Molecular Formula: C₁₅H₁₉NO₅
• Molecular Weight: 293.32
• Mol File: 162504-85-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 493.8°Cat760mmHg
• Flash Point: 252.4°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 1.44E-10mmHg at 25°C
• Refractive Index: 1.57
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-N-CBZ-PIPERIDIN-4-YLOXY)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-CBZ-PIPERIDIN-4-YLOXY)ACETIC ACID(162504-85-0)
• EPA Substance Registry System: 1-N-CBZ-PIPERIDIN-4-YLOXY)ACETIC ACID(162504-85-0)

Safety Data

• Hazardous Substances Data: 162504-85-0(Hazardous Substances Data)

Usage

General Description

1-N-CBZ-PIPERIDIN-4-YLOXY)ACETIC ACID, also known as Z-PIPOVIC ACID, is a chemical compound with the molecular formula C15H19NO5. It is a derivative of piperidine and contains a carboxylic acid group with an acetic acid substitution. 1-N-CBZ-PIPERIDIN-4-YLOXY)ACETIC ACID is commonly used in pharmaceutical research and drug development due to its potential biological activities. It has been studied for its potential use in the treatment of various medical conditions, including neurological disorders and cancer. Additionally, it has been investigated for its potential role in molecular imaging and as a building block in organic synthesis.

InChI:InChI=1/C15H19NO5/c17-14(18)11-20-13-6-8-16(9-7-13)15(19)21-10-12-4-2-1-3-5-12/h1-5,13H,6-11H2,(H,17,18)

Upstream product

• 933477-82-8 [(1-benzyloxycarbonylpiperidin-4-yl)oxy]acetic acid methyl ester 
• 501-53-1 benzyl chloroformate 
• 95798-23-5 1-(benzyloxycarbonyl)-4-hydroxypiperidine 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 144412-43-1 t-Butyl 2-(1-benzyloxycarbonyl-4-piperidyl)oxyacetate 

Downstream Products

• 1174044-50-8 Benzyl 4-(2-(3,3-difluoroazetidin-1-yl)-2-oxoethoxy)piperidine-1-carboxylate 
• 179175-20-3 7-[1-(benzyloxycarbonyl)piperidine-4-yloxyacetylamino]-2-(2-(ethoxycarbonyl)ethyl)-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

Pleuromutilin derivatives having a purine ring. Part 2: Influence of the central spacer on the antibacterial activity against Gram-positive pathogens

Structural modification of the 4-piperidinethio moiety, as a spacer of the first pleuromutilin analogues 2A and 2B having a purine ring, led to discovery of the novel pleuromutilin derivatives 14B and 17B. These compounds with good solubility in water showed promising in vitro antibacterial activity against various Gram-positive bacteria including MRSA, PRSP, and VRE and have potent in vivo efficacy.

Heterocyclic compounds as inhibitors of rotomase enzymes

Compounds of the formula: wherein R1, Y, W, A and R2are as defined above are inhibitors of rotamase enzymes in particular FKBP-12 and FKBP-52. The compounds therefore moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage.

2,3-diaminopropionic acid derivative

The present invention relates to a 2,3-diaminopropionic acid derivative of the formula (1): STR1 or a pharmaceutically acceptable salt thereof. The compounds of the present invention are useful as a platelet aggregation inhibitor, a cancer metastasis inhibitor, a wound healing agent or a bone resorption inhibitor.