162607-15-0

Basic information

• Product Name: 4-Methylthiophene-2-boronic acid
• Synonyms: RARECHEM AH PB 0204;4-METHYLTHIOPHENE-2-BORONIC ACID;4-METHYL-2-THIENYLBORIC ACID;4-METHYL-2-THIENYLBORONIC ACID;4-METHYLTHIOPHENE-2-BORONIC ACID 96%;4-Methylthiophene-2-boronic acid,96%;4-Methylthiophene-2-boronic acid4-Methyl-2-thienylboric acid;(4-methyl-2-thienyl)boronic acid(SALTDATA: 4H2O)
• CAS NO: 162607-15-0
• Molecular Formula: C₅H₇BO₂S
• Molecular Weight: 141.98
• Product Categories: Boronic acids;Boronic acid;Organoborons;Thiophene;Boric Acid| Boric Acid Ester| Potassium Trifluoroborate
• Mol File: 162607-15-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 125-126 °C
• Boiling Point: 305.4 °C at 760 mmHg
• Flash Point: 138.5 °C
• Appearance: White to light beige/Powder
• Density: 1.25 g/cm³
• Vapor Pressure: 0.00036mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: 0-6°C
• PKA: 8.51±0.53(Predicted)
• CAS DataBase Reference: 4-Methylthiophene-2-boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylthiophene-2-boronic acid(162607-15-0)
• EPA Substance Registry System: 4-Methylthiophene-2-boronic acid(162607-15-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41-37/38
• Safety Statements: 37/39-26-39
• HazardClass: IRRITANT, KEEP COLD
• Hazardous Substances Data: 162607-15-0(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow crystal powde

InChI:InChI=1/C5H7BO2S/c1-4-2-5(6(7)8)9-3-4/h2-3,7-8H,1H3

Upstream product

• 53119-60-1 2-bromo-4-methylthiophene 
• 616-44-4 3-Methylthiophene 

Downstream Products

• 945595-80-2 AMG 900 
• 1622306-13-1 C₂₀H₂₀N₄OS 
• 441055-34-1 C₂₆H₃₃N₇S 

Relevant articles and documents

Preparation method of mono-heterocyclic boric acid

The invention provides a preparation method of mono-heterocyclic boric acid. The preparation method comprises steps as follows: (1) a compound shown in a formula I and alkyl borate are dissolved in asolvent A, and a liquor A is obtained; an organic lithium reagent is dissolved in a solvent B, and a liquor B is obtained; the liquor A and the liquor B are subjected to a continuous feeding reaction,the reaction is ended after a product flows out of a reaction pipe, and an intermediate is obtained; (2) the intermediate obtained in the step (1) is subjected to a hydrolysis reaction, and mono-heterocyclic boric acid is obtained. According to the provided preparation method, the reaction yield can be increased and can be up to 95% or above, the reaction time is shortened, the reaction can be completed within 5-60 min, the reaction temperature can be increased, energy consumption of the low-temperature reaction is reduced, the temperature is controllable, the safety is improved, the pressureis convenient to control, the automation degree is improved, production operation is facilitated, the cost is reduced, and the economic benefits are improved.