162609-50-9

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-[3-(4-methylphenyl)-3-oxo-1-propenyl]-, (E)-
• CAS NO: 162609-50-9
• Molecular Formula: C14H12N2O3
• Molecular Weight: 256.261
• Mol File: 162609-50-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[3-(4-methylphenyl)-3-oxo-1-propenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-[3-(4-methylphenyl)-3-oxo-1-propenyl]-, (E)-(162609-50-9)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-[3-(4-methylphenyl)-3-oxo-1-propenyl]-, (E)-(162609-50-9)

Safety Data

• Hazardous Substances Data: 162609-50-9(Hazardous Substances Data)

Upstream product

• 132589-36-7 1-(4-methylphenyl)prop-2-yn-1-ol 
• 4269-94-7 6-iodo-2,4-dioxopyrimidine 

Downstream Products

• 184824-85-9 5-iodo-(E)-6-(2-p-toluoylvinyl)uracil 

Relevant articles and documents

Palladium-catalyzed synthesis of [E]-6-(2-Acylvinyl)uracils and [E]-6-(2-Acylvinyl)-1-[(2-hydroxyethoxy)methyl] uracils - Their antiviral and cytotoxic activities

[E]-6-(2-Acylvinyl)uracils and their corresponding 1-(2-hydroxyethoxy)methyl derivatives were synthesized through palladium-catalyzed reactions which involved an interesting rearrangement. Some of the acylvinyl uracils (3, 4, and 5) and the acyclonucleosides (8 and 10) showed pronounced activity against human T-lymphocyte Molt 4/C8 and CEM cells. However, they were less toxic to murine L1210 and FM3A cells. The compounds did not have any marked antiviral activity.