162681-47-2

Upstream product

• 108-24-7 acetic anhydride 
• 141810-60-8 ethyl 3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside 

Downstream Products

• 1381857-85-7 methyl (2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-glucopyranoside 
• 1198156-15-8 dimethylthexylsilyl O-(2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranosyl)-(1->4)-O-2-azido-3-O-benzyl-6-O-acetyl-2-deoxy-β-D-glucopyranoside 
• 1198156-90-9 N-(benzyl)-benzyloxycarbonyl-5-aminopentyl O-(2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranosyl)-(1->4)-O-2-azido-3-O-benzyl-6-O-levulinoyl-2-deoxy-α-D-glucopyranoside 
• 1198156-88-5 N-(benzyl)-benzyloxycarbonyl-5-aminopentyl O-(2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranosyl)-(1->4)-O-2-azido-3-O-benzyl-6-O-acetyl-2-deoxy-α-D-glucopyranoside 
• 1198156-17-0 dimethylthexylsilyl O-(2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranosyl)-(1->4)-O-2-azido-3-O-benzyl-6-O-levulinoyl-2-deoxy-β-D-glucopyranoside 
• 1053632-38-4 (2S,3S,4S,5R,6R)-3,4-Bis-benzyloxy-6-((2R,4aR,6S,7S,8S,8aR)-8-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy)-5-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 162613-19-6 Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate 
• 162613-18-5 Methyl (ethyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-β-D-glucopyranosid)uronate 
• 162613-20-9 Methyl (ethyl 3,4-di-O-benzyl-2-O-pivaloyl-1-thio-β-D-glucopyranosid)uronate 
• 162613-16-3 Methyl (ethyl 2-O-acetyl-3,4-di-O-benzyl-1-thio-β-D-glucopyranosid)uronate 
• 1055032-87-5 Acetic acid (2S,3R,4S,5S,6S)-4,5-bis-benzyloxy-2-ethylsulfanyl-6-formyl-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

HEPARAN SULFATE SYNTHESIS

The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in

Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies

Although hundreds of heparan sulfate binding proteins have been identified and implicated in a myriad of physiological and pathological processes, very little information is known about the ligand requirements for binding and mediating biological activiti

Synthesis of Methyl (Ethyl 2-O-acyl-3,4-di-O-benzyl-1-thio-β-D-glucopyranosid)uronates and Evaluation of Their Use as Reactive β-Selective Glucuronic Acid Donors

The synthesis of derivatives of methyl (ethyl 2-O-acyl-3,4-di-O-benzyl-1-thio-β-D-glucopyranosid)uronate with different ester groups (acetyl, benzoyl, pivaloyl, and anisoyl) at O-2 is described.The synthesis proceeds via a two-step oxidation (DMSO/DCC fol