162706-06-1 Usage
General Description
2(1H)-Pyrimidinethione, 4,6-diamino-5-methyl- is a chemical compound with the molecular formula C5H8N4S. It is a derivative of pyrimidine and contains two amino groups and a methyl group. 2(1H)-Pyrimidinethione, 4,6-diamino-5-methyl- is widely used in pharmaceutical and agricultural industries due to its various biological activities, such as antiviral, antibiotic, and antitumor properties. It has also been studied for its potential application in the treatment of diseases like cancer, HIV, and bacterial infections. Additionally, 2(1H)-Pyrimidinethione, 4,6-diamino-5-methyl- has been identified as a potential fungicide and is used in various crop protection products to control and prevent fungal diseases in plants.
Check Digit Verification of cas no
The CAS Registry Mumber 162706-06-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,7,0 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 162706-06:
(8*1)+(7*6)+(6*2)+(5*7)+(4*0)+(3*6)+(2*0)+(1*6)=121
121 % 10 = 1
So 162706-06-1 is a valid CAS Registry Number.
162706-06-1Relevant articles and documents
Synthesis and antimicrobial activity of novel 3- [(aminopyrimidiniumyl)thio]methyl cephalosporins
Kim,Lim,Yeo,Bang,Kim,Kim,Woo -,Yang,Oh,Nahm
, p. 3828 - 3833 (2007/10/02)
A series of novel cephalosporin compounds which have 3- [(aminopyrimidiniumyl)thio]methyl substituents was synthesized. They show high antimicrobial activity against various bacterial species including Pseudomonas aeruginosa. Structure-activity relationships with various thiopyrimidines, thiopyrimidiniums, bicyclic thiotriazolopyrimidiniums, and bicyclic thioimidazolopyrimidiniums as 3'-substituents were also studied; cephalosporins with quarternized pyrimidinium moieties have better antimicrobial activities than neuteral pyrimidine cephalosporins, and stabilization of the positive charge on the pyrimidinium moieties is essential for better activity. According to semiempirical PM3 calculations, amino and alkylthio substituents on the pyrimidinium rings play a major role in charge stabilization and delocalization.