3696-36-4

Basic information

• Product Name: 2-METHYLMALONONITRILE
• Synonyms: 2-METHYLMALONITRILE;2-Methylpropanedinitrile;1,1-dicyanoethane;2-Methylmalononitrile;Malononitrile, methyl-;Methyl-malonitril;methyl-malononitril;Methylmalononitrile
• CAS NO: 3696-36-4
• Molecular Formula: C₄H₄N₂
• Molecular Weight: 80.09
• Mol File: 3696-36-4.mol
• Article Data: 26

Chemical Properties

• Melting Point: 36-37 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• Boiling Point: 197.5 °C at 760 mmHg
• Flash Point: 81.8 °C
• Appearance: /
• Density: 0.98 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 2-METHYLMALONONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLMALONONITRILE(3696-36-4)
• EPA Substance Registry System: 2-METHYLMALONONITRILE(3696-36-4)

Safety Data

• Hazardous Substances Data: 3696-36-4(Hazardous Substances Data)

Usage

General Description

2-Methylmalononitrile is a chemical compound with the molecular formula C4H5N. It is a colorless liquid with a faint odor, and it is commonly used as a reactant in organic synthesis. 2-METHYLMALONONITRILE is important in the production of pharmaceuticals and agricultural chemicals, as well as in the manufacturing of dyes and pigments. It can also be used as an intermediate in the production of other chemical compounds. 2-Methylmalononitrile is known for its versatile reactivity and is a useful building block in organic chemistry. However, it is important to handle it with care, as it can be toxic and irritating to the skin and respiratory system.

InChI:InChI=1/C9H8BNO2/c12-10(13)9-8-4-2-1-3-7(8)5-6-11-9/h1-6,12-13H

Upstream product

• 773837-37-9 sodium cyanide 
• 6839-20-9 2-[(methylsulfonyl)oxy]propanenitrile 
• 7039-38-5 (Methyl-phenyl-sulfonium)-dicyanmethylid 
• 1113-63-9 2-methyl-malonamide 
• 71565-78-1 2-cyanopropionamide 
• 74-83-9 methyl bromide 
• 109-77-3 malononitrile 
• 77928-77-9 2-methyl-1,4-butanediamide 
• 74-88-4 methyl iodide 
• 50-00-0 formaldehyd 
• 138976-63-3 methyliodomalononitrile 
• 85688-96-6 Methyl(1,1,2-trimethylpropyl)malonsaeuredinitril 
• 24850-33-7 allyltributylstanane 
• 85688-94-4 (1,1-Dimethylpropyl)methylmalonsaeuredinitril 

Downstream Products

• 6802-57-9 9,10-dihydro-9,10-ethano-anthracene-11,11-dicarbonitrile 
• 2400-78-4 1,3-diamino-2-methylpropane 
• 89182-81-0 2-bromo-2-cyanopropionitrile 
• 162706-06-1 4,6-diamino-5-methyl-1H-pyrimidine-2-thione 
• 21954-82-5 (tert-Butyl)(methyl)malononitril 
• 23054-41-3 methyl-(2,4,6-triphenyl-6H-[1,3]oxazin-6-yl)-malononitrile 
• 72632-65-6 4-methyl-5-aminothiazole 
• 7765-74-4 (2-cyano-1-chloro-propenyl)-phosphorimidic acid trichloride 
• 7713-07-7 1,1,2-Trichlor-2-cyan-N-trichlorphosphoronyliden-propylamin 
• 7713-03-3 2,2,4,6-tetrachloro-5-methyl-2λ⁵-[1,3,2]diazaphosphinine 
• 10517-95-0 Methylsulfonyl-methyl-malodinitril 
• 50997-04-1 p-Xylylenbis(methylmalonnitril) 
• 154657-02-0 2-allyl-2-methylmalononitrile 

Relevant articles and documents

Copper-Catalyzed Cross-Nucleophile Coupling of β-Allenyl Silanes with Tertiary C-H Bonds: A Radical Approach to Branched 1,3-Dienes

Described herein is a distinctive approach to branched 1,3-dienes through oxidative coupling of two nucleophilic substrates, β-allenyl silanes, and hydrocarbons appending latent functionality by copper catalysis. Notably, C(sp3)-H dienylation proceeded in a regiospecific manner, even in the presence of competitive C-H bonds that are capable of occurring hydrogen atom transfer process, such as those located at benzylic and other tertiary sites, or adjacent to an oxygen atom. Control experiments support the intermediacy of functionalized alkyl radicals.

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a preparation method of nitrile. Compared with the prior art, the preparation method has the characteristics of obvious reduction of the usage amount of ammonia sources, low environmental pressure, low energy consumption, low production cost, high purity and yields of nitrile products, and the like, and can be used for obtaining nitrile with a more complex structure. The invention also relates to a method for preparing corresponding amine with nitrile.

2 - methyl malonic acid diester synthetic method of the compound

The invention discloses a synthetic method of 2-diester methylmalonate compounds, and relates to the technical field of carboxylic ester preparation. The synthetic method comprises steps as follows: C, sulfonic acid 2-ethyl N-cyanoethanimideate IV and cyanide react under the action of a solvent and a catalyst, and 2-methyl malononitrile V is obtained; D, 2-methyl malononitrile V and ROH react under the action of the solvent and concentrated sulfuric acid, and products of 2-diester methylmalonate compounds I are obtained, wherein MCN is cyanide, M is Na or K, ROH is alkyl alcohol, alkenyl alcohol or a fluoride group containing alcohol, is benzyl alcohol or benzyl alkyl, halogen or nitro substituted benzyl alcohol, or is phenol or C1-C5 containing alkyl, halogen or nitro substituted phenol. The method is unique, the reaction conditions are mild, the reaction process is basically free of by-products, the yield is high, adopted raw materials have extensive sources, and acetaldehyde can be used as the raw material; the synthetic method is applicable to industrial production.