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N-(2-Methylpropyl)-N'-phenylthiourea is a chemical compound that belongs to the class of thioureas, which are derivatives of urea. It is characterized by its white to off-white crystalline solid appearance and its solubility in organic solvents. N-(2-Methylpropyl)-N'-phenylthiourea has a diverse range of applications, including its use as a rubber vulcanization accelerator, in the production of pharmaceuticals and agricultural chemicals, and has been investigated for its potential antidiabetic and antioxidant properties. However, due to its potential hazards, including harmful effects if swallowed, inhaled, or absorbed through the skin, and its ability to cause irritation to the eyes, skin, and respiratory tract, it requires careful handling and appropriate safety measures.

16275-53-9

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16275-53-9 Usage

Uses

Used in Rubber Industry:
N-(2-Methylpropyl)-N'-phenylthiourea is used as a rubber vulcanization accelerator for enhancing the process of vulcanization, which is essential for improving the strength and elasticity of rubber products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, N-(2-Methylpropyl)-N'-phenylthiourea serves as a key intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agricultural Chemicals:
N-(2-Methylpropyl)-N'-phenylthiourea is also utilized in the production of agricultural chemicals, playing a role in enhancing crop protection and yield.
Used in Research for Antidiabetic Properties:
N-(2-Methylpropyl)-N'-phenylthiourea is studied for its potential antidiabetic properties, indicating a possible use in the development of treatments for diabetes.
Used in Research for Antioxidant Properties:
Additionally, it has been investigated for its antioxidant potential, which may lead to applications in the health and wellness industry, as antioxidants are known to protect against cellular damage caused by free radicals.
Safety Precautions:
When working with N-(2-Methylpropyl)-N'-phenylthiourea, it is crucial to follow proper safety protocols to prevent harm. This includes avoiding ingestion, inhalation, or skin absorption, as well as taking measures to prevent eye and skin irritation and respiratory tract issues.

Check Digit Verification of cas no

The CAS Registry Mumber 16275-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,7 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16275-53:
(7*1)+(6*6)+(5*2)+(4*7)+(3*5)+(2*5)+(1*3)=109
109 % 10 = 9
So 16275-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2S/c1-9(2)8-12-11(14)13-10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3,(H2,12,13,14)

16275-53-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-methylpropyl)-3-phenylthiourea

1.2 Other means of identification

Product number -
Other names N-Phenyl-N'-isobutylthiourea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16275-53-9 SDS

16275-53-9Relevant academic research and scientific papers

Zn, Cd and Hg complexes with unsymmetric thiourea derivatives; syntheses, free radical scavenging and enzyme inhibition essay

Rahman, Faizan Ur,Bibi, Maryam,Altaf, Ataf Ali,Tahir, Muhammad Nawaz,Ullah, Farhat,Zia-Ur-Rehman,Khan, Ezzat

, (2020/04/15)

Unsymmetrical thiourea of general formula RR'C[dbnd]S where R ≠ R′, were prepared by treating phenyisothiocayanate with iso-butylamine and tert-butylamine and respective thiourea derivatives, isobutylphenylthiourea (1) and tert-butylphenylthiourea (2) wer

Synthesis of metronidazole based thiazolidinone analogs as promising antiamoebic agents

Ansari, Mohammad Fawad,Inam, Afreen,Ahmad, Kamal,Fatima, Shehnaz,Agarwal, Subhash M.,Azam, Amir

supporting information, (2020/10/12)

Metronidazole and its derivatives are widely used for the treatment of amoebiasis. However, metronidazole is considered as the standard drug but it has many side effects. The present study describes the synthesis of a series of metronidazole based thiazolidinone analogs via Knoevenagel condensation of 4-[2-(2-methyl-5-nitro-1H-imidazole-1-yl)ethoxy]benzaldehyde 1 with various thiazolidinone derivatives 2–14 to get the new scaffold (15–27) having better activity and lesser toxicity. Six compounds have shown better efficacy and lesser cytotoxicity than the standard drug metronidazole towards HM1: IMSS strain of Entamoeba histolytica. These compounds may combat the problem of drug resistance and might be effective in identifying potential alternatives for future drug discovery against EhOASS.

Synthesis, characterization and structure optimization of a series of thiazolidinone derivatives as Entamoeba histolytica inhibitors

Mushtaque, Md.,Avecilla, Fernando,Azam, Amir

, p. 439 - 448 (2012/11/07)

A series of thiazolidinone derivatives were synthesized by sodium acetate assisted cyclization of 1-isobutyl-3-phenylthiourea with chloroacetic acid followed by the piperidine facilitated substitution of the resulting thiazolidinone with different substit

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