16275-53-9

Usage

Uses

Used in Rubber Industry:
N-(2-Methylpropyl)-N'-phenylthiourea is used as a rubber vulcanization accelerator for enhancing the process of vulcanization, which is essential for improving the strength and elasticity of rubber products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, N-(2-Methylpropyl)-N'-phenylthiourea serves as a key intermediate in the synthesis of various drugs, contributing to the development of new medicinal compounds.
Used in Agricultural Chemicals:
N-(2-Methylpropyl)-N'-phenylthiourea is also utilized in the production of agricultural chemicals, playing a role in enhancing crop protection and yield.
Used in Research for Antidiabetic Properties:
N-(2-Methylpropyl)-N'-phenylthiourea is studied for its potential antidiabetic properties, indicating a possible use in the development of treatments for diabetes.
Used in Research for Antioxidant Properties:
Additionally, it has been investigated for its antioxidant potential, which may lead to applications in the health and wellness industry, as antioxidants are known to protect against cellular damage caused by free radicals.
Safety Precautions:
When working with N-(2-Methylpropyl)-N'-phenylthiourea, it is crucial to follow proper safety protocols to prevent harm. This includes avoiding ingestion, inhalation, or skin absorption, as well as taking measures to prevent eye and skin irritation and respiratory tract issues.

InChI:InChI=1/C11H16N2S/c1-9(2)8-12-11(14)13-10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3,(H2,12,13,14)

Upstream product

• 78-81-9 isobutylamine 
• 103-72-0 phenyl isothiocyanate 
• 62-53-3 aniline 

Downstream Products

• 1400583-90-5 C₂₀H₁₉ClN₂OS 
• 1400583-92-7 C₂₁H₁₉F₃N₂OS 
• 1400583-94-9 C₂₂H₂₅N₃OS 
• 1400583-97-2 C₂₀H₂₀N₂O₂S 
• 1400583-98-3 C₂₂H₂₄N₂O₃S 
• 1400584-00-0 C₂₁H₂₂N₂O₂S 
• 1400584-02-2 C₂₁H₂₂N₂OS 
• 1400584-04-4 C₂₀H₂₀N₂O₂S 
• 1400584-06-6 C₂₁H₂₀N₂O₃S 
• 1400584-07-7 C₁₉H₁₉N₃OS 
• 1400584-09-9 C₁₉H₂₀N₂OS₂ 
• 1400584-11-3 C₂₁H₂₂N₂O₃S 
• 1400584-12-4 C₂₀H₁₉ClN₂OS 
• 1400584-14-6 C₂₂H₂₄N₂O₃S 

Relevant academic research and scientific papers

Zn, Cd and Hg complexes with unsymmetric thiourea derivatives; syntheses, free radical scavenging and enzyme inhibition essay

Unsymmetrical thiourea of general formula RR'C[dbnd]S where R ≠ R′, were prepared by treating phenyisothiocayanate with iso-butylamine and tert-butylamine and respective thiourea derivatives, isobutylphenylthiourea (1) and tert-butylphenylthiourea (2) wer

Synthesis of metronidazole based thiazolidinone analogs as promising antiamoebic agents

Metronidazole and its derivatives are widely used for the treatment of amoebiasis. However, metronidazole is considered as the standard drug but it has many side effects. The present study describes the synthesis of a series of metronidazole based thiazolidinone analogs via Knoevenagel condensation of 4-[2-(2-methyl-5-nitro-1H-imidazole-1-yl)ethoxy]benzaldehyde 1 with various thiazolidinone derivatives 2–14 to get the new scaffold (15–27) having better activity and lesser toxicity. Six compounds have shown better efficacy and lesser cytotoxicity than the standard drug metronidazole towards HM1: IMSS strain of Entamoeba histolytica. These compounds may combat the problem of drug resistance and might be effective in identifying potential alternatives for future drug discovery against EhOASS.

Synthesis, characterization and structure optimization of a series of thiazolidinone derivatives as Entamoeba histolytica inhibitors

A series of thiazolidinone derivatives were synthesized by sodium acetate assisted cyclization of 1-isobutyl-3-phenylthiourea with chloroacetic acid followed by the piperidine facilitated substitution of the resulting thiazolidinone with different substit