162792-92-9Relevant articles and documents
Retinoids and related compounds. Part 19. Syntheses of 9E- and 9Z-locked retinoic acid analogues and their transcriptional activities as ligands for retinoic acid receptors and retinoid X receptors
Katsuta, Yuko,Aoyama, Yukiko,Osone, Hisa,Wada, Akimori,Ito, Masayoshi
, p. 1405 - 1410 (2007/10/03)
Novel retinoic acid (RA) analogues, 9E-locked-RA 3 and 9Z-locked RA 4, have been synthesized in order to prohibit geometrical isomerization at the C(9)-C(10) double bond when these ligands interact with the retinoic acid receptor (RAR) and retinoid X rece
Synthesis of 9E- and 9Z-locked retinoic acid analogs as ligands for RAR and RXR
Katsuta,Aoyama,Osone,Wada,Uchiyama,Kitamoto,Masushige,Kato,Ito
, p. 2659 - 2661 (2007/10/02)
New retinoic acid (RA) analogs 9E-locked-RA 3 and 9Z-locked-RA 4 were synthesized from dithiane 6 and β-cyclocitral 13, respectively. Both analogs behaved as agonistic ligands for a mixture of retinoic acid receptor (RAR) and retinoid X receptor (RXR).