162792-89-4

Upstream product

• 117360-96-0 3-<(1-methylpropyl)oxy>-2-cyclohexen-1-one 
• 191278-80-5 3-sec-Butoxy-6-[hydroxy-(2,6,6-trimethyl-cyclohex-1-enyl)-methyl]-cyclohex-2-enone 
• 432-25-7 2,6,6-trimethylcyclohex-1-enecarbaldehyde 
• 917-54-4 methyllithium 

Downstream Products

• 162792-91-8 Acetic acid (2-methyl-4-oxo-cyclohex-2-enyl)-(2,6,6-trimethyl-cyclohex-1-enyl)-methyl ester 
• 162792-95-2 Ethyl (E,E,E)-3-methyl-4-<3-methyl-4-<(2,6,6-trimethylcyclohex-1-enyl)methylene>cyclohex-2-enylidene>but-2-enoate 
• 162792-94-1 Ethyl (E,E,Z)-3-methyl-4-<3-methyl-4-<(2,6,6-trimethylcyclohex-1-enyl)methylene>cyclohex-2-enylidene>but-2-enoate 
• 162792-92-9 (E,E)-3-<3-Methyl-4-<(2,6,6-trimethylcyclohex-1-enyl)methylene>cyclohex-2-enylidene>propan-2-one 
• 162792-90-7 (E)-3-Methyl-4-<(2,6,6-trimethylcyclohex-1-enyl)methylene>cyclohex-2-enone 

Relevant academic research and scientific papers

Retinoids and related compounds. Part 19. Syntheses of 9E- and 9Z-locked retinoic acid analogues and their transcriptional activities as ligands for retinoic acid receptors and retinoid X receptors

Novel retinoic acid (RA) analogues, 9E-locked-RA 3 and 9Z-locked RA 4, have been synthesized in order to prohibit geometrical isomerization at the C(9)-C(10) double bond when these ligands interact with the retinoic acid receptor (RAR) and retinoid X rece

Synthesis of 9E- and 9Z-locked retinoic acid analogs as ligands for RAR and RXR

New retinoic acid (RA) analogs 9E-locked-RA 3 and 9Z-locked-RA 4 were synthesized from dithiane 6 and β-cyclocitral 13, respectively. Both analogs behaved as agonistic ligands for a mixture of retinoic acid receptor (RAR) and retinoid X receptor (RXR).