162819-98-9Relevant academic research and scientific papers
MORPHINAN DERIVATIVES AS ANTI-ITCHING AGENT
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Page/Page column 41, (2008/06/13)
A novel antipruritic useful for the treatment of pruritus accompanying various diseases is disclosed. The antipruritic comprises a specific morphinan derivative having a nitrogen-containing cyclic group or the pharmaceutically acceptable acid addition salt thereof such as N-(17-cyclopropylmethyl-4,5±-epoxy-3,14-dihydroxy-morphinan-62-yl)-phthalimide hydrochloric acid salt or N-( 17-cyclopropylmethyl-4,5±-epoxy-3,14-dihydroxy-morphinan-62-yl)-3,4,5,6-tetrahydrophthalimide tartaric acid salt.
