1628223-79-9

Upstream product

• 1210046-23-3 1-(4-bromophenyl)-2-(4-phenyl-1H-1,2,3-triazole-1-yl)-1-ethanone 
• 87-48-9 5-Bromo-1H-indole-2,3-dione 
• 109-77-3 malononitrile 
• 99-73-0 para-bromophenacyl bromide 
• 536-74-3 phenylacetylene 

Relevant academic research and scientific papers

InCl3-mediated eco-friendly three-component domino reaction for synthesis of highly functionalized triazolylspiroxindolinopyrans and triazolylpyrans under solvent-free conditions

A one pot domino protocol has been developed for the efficient synthesis of novel triazolylspiroxindolinopyrans and triazolylpyran derivatives. The synthesis was achieved by reacting phenacyltriazole, isatin/aromatic aldehyde and active methylene compounds in the presence of InCl3 under solvent-free conditions at 100 °C. This novel strategy affording biologically relevant heterocyclic compounds presumably involves Knoevenagel condensation/Michael addition/6-exo-dig-cyclisation sequences. the Partner Organisations 2014.