162854-89-9

Basic information

• Product Name: 2-(1-chloro-4-methoxybutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 162854-89-9
• Molecular Formula: C₁₁H₂₂BClO₃
• Molecular Weight: 248.5546
• Mol File: 162854-89-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 268.5°C at 760 mmHg
• Flash Point: 116.2°C
• Density: 1.01g/cm³
• Vapor Pressure: 0.0127mmHg at 25°C
• Refractive Index: 1.438
• CAS DataBase Reference: 2-(1-chloro-4-methoxybutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-chloro-4-methoxybutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(162854-89-9)
• EPA Substance Registry System: 2-(1-chloro-4-methoxybutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(162854-89-9)

Safety Data

• Hazardous Substances Data: 162854-89-9(Hazardous Substances Data)

Upstream product

• 667917-13-7 2-(3-methoxypropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 75-09-2 dichloromethane 

Relevant articles and documents

BORONATE MEDICAMENTS FOR PREVENTING THROMBOSIS DURING SURGERY

The use for the manufacture of a medicament for preventing unwanted coagulation during surgery, and particularly a Coronary Artery Bypass Graft (CABG) procedure, of boronic acids of formula (I), and salts, prodrugs and prodrug salts thereof; wherein Y com

BORONIC ACID THROMBIN INHIBITORS

A thrombin inhibitor selected from boronic acids of formula (I), and salts, prodrugs and prodrug salts thereof: wherein X is H (to form NH2) or an amino-protecting group; aal is an amino acid residue having a side chain selected from formula (A) and (B)-(CO)a-(CH2)b-Dc-(CH2)d-E (A), -(CO)a-(CH2)b-Dc-Ce(E1)(E2)(E3) wherein E1, E2 and E3 ore 5-6 membered saturated or unsaturated hydrocarbyl rings, or one of E1 , E2 and E3 is hydrogen and the other two are a said hydrocarbyl ring, E, E1, E2 and E3 optionally being halogenated when saturated and mandatorily being halogenated when unsaturated, a particular halogen being fluorine; aa2 is a residue of an amino acid which binds to the thrombin S2 subsite; and R9 is a straight chain alkyl group interrupted by one or more ether linkages or R9 is -(CH2)m W and W is -OH or halogen.