1628708-89-3

Upstream product

• 31039-85-7 1-(2',4',6'-tri-tert-butylphenyl)acetylene 
• 1618099-90-3 [2-D]-1-(2,4,6-tri-tert-butylphenyl)acetylene 
• 1618100-32-5 diethyl 1-(2',4',6'-tri-tert-butylphenyl)vinyl phosphate 
• 3975-77-7 1-bromo-2,4,6-tri-tert-butylbenzene 
• 66415-27-8 2,4,6-tri-tert-butylbenzoic acid 
• 22744-29-2 1-(2,4,6-tri-tert-butylphenyl)ethan-1-one 
• 20208-55-3 2,4,6-tri-tert-butylbenzoyl chloride 

Relevant academic research and scientific papers

Highly syn selective addition of aqueous HBr to hydrophobically shielded arylalkynes

Hydrophobically shielded alkynes HC≡C-aryl, carrying 2,6-di- and 2,4,6-tri-tert-butylphenyl as the aryl group, can add aqueous HBr on heating in moist chloroform solutions to produce pure H2C=C(-Br)-aryl (isolated yields 96%, no hydrolysis). Em

Highly syn selective addition of aqueous HBr to hydrophobically shielded arylalkynes

Hydrophobically shielded alkynes HCC-aryl, carrying 2,6-di- and 2,4,6-tri-tert-butylphenyl as the aryl group, can add aqueous HBr on heating in moist chloroform solutions to produce pure H2CC(-Br)-aryl (isolated yields 96%, no hydrolysis). Employment of DCC-aryl furnished initially only the E stereoisomer of DHCC(-Br)-aryl (stereospecific syn addition), which was slowly both dedeuteriated and partially transformed to the Z stereoisomer by HBr. The strongly retarded HBr addition to H3C-CC-aryl in moist chloroform produced again more E than Z product, whereas a thermodynamic E/Z ratio of 10:87 was found in moist acetic acid. Substitution of Br by LiSnMe3produced H2CC(-SnMe3)-aryl with well resolved long range 119Sn NMR coupling constants.