3975-77-7

Basic information

• Product Name: 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE
• Synonyms: Bromobenzene, 2,4,6-tri-tert-butyl-;1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE;1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE 97+%;1-BroMo-2,4,6-tri-tert-butylbenzene 97%;Bromo(1,3,5-tris-tert-butyl)benzene;NSC 133894;2,4,6-Tri-tert-butylphenyl bromide
• CAS NO: 3975-77-7
• Molecular Formula: C₁₈H₂₉Br
• Molecular Weight: 325.33
• Product Categories: Aryl;C13 to C37+;Halogenated Hydrocarbons
• Mol File: 3975-77-7.mol
• Article Data: 10

Chemical Properties

• Melting Point: 168-173 °C(lit.)
• Boiling Point: 299.7°Cat760mmHg
• Flash Point: 123.7°C
• Appearance: /
• Density: 1.064g/cm³
• Vapor Pressure: 0.00209mmHg at 25°C
• Refractive Index: 1.494
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 1913257
• CAS DataBase Reference: 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE(3975-77-7)
• EPA Substance Registry System: 1-BROMO-2,4,6-TRI-TERT-BUTYLBENZENE(3975-77-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 3975-77-7(Hazardous Substances Data)

Usage

Uses

1-Bromo-2,4,6-tri-tert-butylbenzene was used in the synthesis of bulky biarylphosphine ligand. This ligand was reported to participate in the Pd-catalyzed C-O cross-coupling of a wide range of aryl halides and phenols under milder conditions. It was used to investigate the effect on oligomerization of increased steric bulk in dimethylindium(III) chalcogenolates. It may be used to form α,α-dimethyl-β-phenyl hydrostyrene by reacting with phenylboronic acid.

General Description

1-Bromo-2,4,6-tri-tert-butylbenzene (2,4,6-tri-tert-butylbromobenzene) is a hindered aryl bromide. 1-Bromo-2,4,6-tri-tert-butylbenzene on reaction with phenylboronic acid yields α,α-dimethyl-β-phenyl hydrostyrene.

InChI:InChI=1/C18H29Br/c1-16(2,3)12-10-13(17(4,5)6)15(19)14(11-12)18(7,8)9/h10-11H,1-9H3

Upstream product

• 40782-34-1 tris-(tert-butyl)benzene 
• 1460-02-2 1,3,5-Tri-tert-butylbenzene 
• 71-43-2 benzene 
• 35383-91-6 2,4,6-tri-tert-butylphenyllithium 
• 13465-74-2 bromo trichloro silane 
• 7726-95-6 bromine 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 83466-54-0 Bis(2,4,6-tri-tert-butylphenyl)diphosphen 

Downstream Products

• 17799-06-3 (2,4,6-tri-t-butyl)benzyl alcohol 
• 1222-01-1 1,3,5-tris-tert-butyl toluene 
• 99789-89-6 2,4,6-tri-(tert-butyl)phenyltrifliorosilane 
• 24309-22-6 2,4,6-tri-(tert-butyl)benzonitrile 
• 182227-53-8 C₁₉H₃₂ClP 
• 182227-55-0 C₂₁H₃₆ClP 
• 83466-59-5 C₂₇H₄₀ClP 
• 83115-14-4 meso-bis(2,4,6-tri-tert-butylphenyl)diphosphene 
• 154393-74-5 C-Phenyl-C-(2,4,6-tri-tert-butyl-phenyl)-methyleneamine 
• 151984-82-6 benzo-3-(2,4,6-tri-tert-butylphenyl)-1,3,2-dioxaphospholane 
• 1460-02-2 1,3,5-Tri-tert-butylbenzene 
• 190438-01-8 1-(2',4',6'-tri-tert-butylphenyl)-3-methyl-phosphole 
• 190438-03-0 1-(2,4,6-tri-tert-butylphenyl)-3-methyl-3-phospholene 1-oxide 

Relevant articles and documents

Reactivity of phospha-Wittig reagents towards NHCs and NHOs

Phospha-Wittig reagents, RPPMe3(R = Mes* 2,4,6-tBu3-C6H2;MesTer 2,6-(2,4,6-Me3C6H2)-C6H3;DipTer 2,6-(2,6-iPr2C6H

Mechanistic studies of adamantylacetophenones with competing reaction pathways in solution and in the crystalline solid state

Photochemical reactions in crystals occur under conditions of highly restricted molecular mobility such that only one product is generally obtained, even when there are many others that can be observed in the gas phase or in solution. A series of 2-(1-ada

Functionalization of P4 using a Lewis acid stabilized bicyclo[1.1.0]tetraphosphabutane anion

Reacting white phosphorus (P4) with sterically encumbered aryl lithium reagents (aryl=2,6-dimesitylphenyl or 2,4,6-tBu3C6H2) and B(C6F5)3 gives the unique, isolable Lewis acid st