16289-13-7 Usage
Uses
Used in Pharmaceutical Industry:
Chlorthalidone Impurity G is used as an antihypertensive agent for the treatment of high blood pressure. It functions by inhibiting the Na+/Clcotransporter in the distal convoluted tubule of the kidney, which prevents the reabsorption of sodium and chloride, leading to a reduction in plasma volume and cardiac output. Additionally, it inhibits carbonic anhydrase (CA), contributing to its sustained vasodilatory activity.
Furthermore, Chlorthalidone Impurity G is used in formulations containing chlorthalidone, which can be used alone or in combination with other antihypertensive agents to lower arterial blood pressure. It also serves as an adjuvant to address edema caused by cardiac or renal disorders.
In Preclinical Research:
Chlorthalidone Impurity G is used in dietary administration to reduce arterial hypertension and prevent or reduce ventricular hypertrophy in DOCA-salt hypertensive rats, providing valuable insights into the development of new antihypertensive treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 16289-13-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,8 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16289-13:
(7*1)+(6*6)+(5*2)+(4*8)+(3*9)+(2*1)+(1*3)=117
117 % 10 = 7
So 16289-13-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H9Cl2NO2/c15-11-6-5-8(7-12(11)16)14(19)10-4-2-1-3-9(10)13(18)17-14/h1-7,19H,(H,17,18)
