1628935-01-2Relevant academic research and scientific papers
Asymmetric Synthesis of a Fused Tricyclic Hydronaphthofuran Scaffold by Desymmetric [2+2+2] Cycloaddition
Teng, Qi,Mao, Wenxiu,Chen, Dong,Wang, Zhen,Tung, Chen-Ho,Xu, Zhenghu
supporting information, p. 2220 - 2224 (2020/01/24)
A rhodium(I)-BINAP-catalyzed highly enantioselective [2+2+2] cycloaddition of enynes with alkynes has been developed. Diverse fused tricyclic hydronaphthofuran scaffolds with three consecutive stereogenic centers were constructed in one step from easily a
Palladium enolate umpolung: Cyclative diacetoxylation of alkynyl cyclohexadienones promoted by a Pd/SPRIX catalyst
Takenaka, Kazuhiro,Mohanta, Suman C.,Sasai, Hiroaki
supporting information, p. 4675 - 4679 (2014/05/20)
A novel palladium-catalyzed reaction involving an unusual nucleophilic attack on a palladium enolate was developed using a spiro-bis(isoxazoline) (SPRIX) ligand. Treatment of alkynyl cyclohexadienone substrates with a Pd/SPRIX catalyst in acetic acid under an oxygen atmosphere furnished diacetoxylated benzofuranone derivatives in good yields. This cyclative diacetoxylation proceeded enantioselectively in the presence of an optically pure SPRIX ligand. In a SPRIX: A new palladium-catalyzed reaction involving an unusual nucleophilic attack on a palladium enolate was developed using the SPRIX ligand. Treatment of alkynyl cyclohexadienone substrates with Pd/SPRIX in acetic acid under an oxygen atmosphere furnished diacetoxylated benzofuranone derivatives in good yields and with high enantioselectivity.
