1629211-99-9Relevant academic research and scientific papers
Enantioselective organocatalytic conjugate addition of alkenes to α,β-enones
Cui, Lingyun,Zhang, Long,Luo, Sanzhong,Cheng, Jin-Pei
supporting information, p. 3540 - 3545 (2014/06/23)
We report the first example of the enantioselective conjugate addition of alkenes (aromatic enamines) to enones catalyzed by chiral primary amines. The reactions encompass a plethora of α,β-enones including difficult α-substituted vinyl ketones to give vinylation adducts in high yields with good enantioselectivity. The methodology is of synthetic potential in accessing chiral functional materials. Copyright
