62834-89-3Relevant academic research and scientific papers
Transition-Metal-Free Reductive Deoxygenative Olefination with CO2
Zhu, Dao-Yong,Li, Wen-Duo,Yang, Ce,Chen, Jie,Xia, Ji-Bao
, p. 3282 - 3285 (2018/06/11)
A new transition-metal-free reductive deoxygenative olefination of phosphorus ylides with CO2, an abundant and sustainable C1 chemical feedstock, is described. This catalytic CO2 fixation afforded β-unsubstituted acrylates and vinyl ketones in good yields with broad scope and good functional group tolerance under mild reaction conditions. Cost-effective and easily handled polymethylhydrosiloxane was used as a reductant. Bis(silyl)acetal was proved to be the key intermediate in this reductive functionalization of CO2.
A methylene compound of preparation method and its application (by machine translation)
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Paragraph 0023-0024; 0031-0032; 0052-0054, (2017/11/16)
The invention discloses a methylene compound of preparation method and its application, relates to the field of organic synthesis, the process comprises: 1) in the presence of a three-valent metal salt catalyst, will arone compound and halogen methyl radical trialkyl ammonium salt dissolved in a solvent, 2) 80 - 130 °C reaction 1 - 4 hours, separated and purified α - the methyl radical is fragrant compounds, the reaction environment pollution is small, substrate and wide range of application. (by machine translation)
Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides
Jin, Xiongjie,Kataoka, Kengo,Yatabe, Takafumi,Yamaguchi, Kazuya,Mizuno, Noritaka
supporting information, p. 7212 - 7217 (2016/07/06)
Although the α-oxygenation of amines is a highly attractive method for the synthesis of amides, efficient catalysts suited to a wide range of secondary and tertiary alkyl amines using O2as the terminal oxidant have no precedent. This report describes a novel, green α-oxygenation of a wide range of linear and cyclic secondary and tertiary amines mediated by gold nanoparticles supported on alumina (Au/Al2O3). The observed catalysis was truly heterogeneous, and the catalyst could be reused. The present α-oxygenation utilizes O2as the terminal oxidant and water as the oxygen atom source of amides. The method generates water as the only theoretical by-product, which highlights the environmentally benign nature of the present reaction. Additionally, the present α-oxygenation provides a convenient method for the synthesis of18O-labeled amides using H218O as the oxygen source.
Kinetic resolution of aryl alkenylcarbinols catalyzed by Fc-PIP
Hu, Bin,Meng, Meng,Jiang, Shanshan,Deng, Weiping
, p. 1289 - 1294 (2012/08/28)
An effective kinetic resolution of a variety of aryl alkenylcarbinols catalyzed by nonenzymatic acyl transfer catalyst Fc-PIP was developed, affording corresponding unreacted alcohols in good to excellent ee value up to 99% and with selectivity factors up to 24.
Synthesis of α-indanones via intramolecular direct arylation with cyclopropanol-derived homoenolates
Rosa, David,Orellana, Arturo
scheme or table, p. 1922 - 1924 (2012/03/11)
A palladium-catalysed, tandem cyclopropanol rearrangement and direct arylation approach for the synthesis of 1-indanones is reported. The reaction is generally high yielding, uses oxygen as the terminal oxidant and tolerates a range of functional groups on the aryl ring.
Thermal retro-aldol reaction using fluorous ether F-626 as a reaction medium
Fukuyama, Takahide,Kawamoto, Takuji,Okamura, Takahiro,Denichoux, Aurelien,Ryu, Ilhyong
experimental part, p. 2193 - 2196 (2010/10/21)
A high-boiling, fluorous-organic hybrid ether, F-626, was tested for use in thermal retro-aldol reactions and found to be an excellent reaction medium in view of the ease of separation from the product by fluorous/organic biphasic treatment. The recovered F-626 can be readily reused for subsequent runs.
