Cas 162941-64-2,4-[4-(1-Amino-ethyl)-phenyl]-butyric acid methyl ester

162941-64-2

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Basic information

Product Name: 4-[4-(1-Amino-ethyl)-phenyl]-butyric acid methyl ester
Synonyms: 4-[4-(1-Amino-ethyl)-phenyl]-butyric acid methyl ester
CAS NO:162941-64-2
Molecular Formula:
Molecular Weight: 221.299
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-[4-(1-Amino-ethyl)-phenyl]-butyric acid methyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 4-[4-(1-Amino-ethyl)-phenyl]-butyric acid methyl ester(162941-64-2)
EPA Substance Registry System: 4-[4-(1-Amino-ethyl)-phenyl]-butyric acid methyl ester(162941-64-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 162941-64-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 162941-64-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,9,4 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 162941-64:
(8*1)+(7*6)+(6*2)+(5*9)+(4*4)+(3*1)+(2*6)+(1*4)=142
142 % 10 = 2
So 162941-64-2 is a valid CAS Registry Number.

162941-64-2Upstream product

162941-64-2Downstream Products

162938-58-1 methyl 4-[4-[1-(4-chlorophenylsulfonylamino)ethyl]phenyl]butyrate

162941-64-2Relevant academic research and scientific papers

Synthesis and dual antagonistic activity against thromboxane A2 and leukotriene D4 of [4-[1-(benzenesulfonamido)alkyl]phenyl]alkanoic acid derivatives

Sakurai, Shunichiro,Ogawa, Nobuo,Onogi, Yasuyo,Takeshita, Makoto,Takahashi, Hiromi,Ohashi, Tetsuo,Kato, Ken-Ichi,Yasuda, Shingo,Kato, Hideo

, p. 849 - 862 (2007/10/03)

In order to find new antiasthmatic agents with dual antagonistic activity against thromboxane A2 (TXA2) and leukotriene D4 (LTD4) receptors, synthesis and pharmacological evaluation of various [4-[1- (benzenesulfonamido)-alkyl]phenyl]alkanoic acid derivatives were undertaken. TXA2 and LTD4 antagonistic activities in vitro were evaluated by measuring the inhibitory effects on U-46619-induced contraction of guinea-pig trachea and LTD4-induced contraction of guinea-pig ileum and trachea. Several compounds showed satisfactory dual antagonistic activities, and their effect (after oral administration) on LTD4-induced bronchoconstriction in guinea- pig in vivo was examined. The results demonstrated that both 4-[4-[1-(4- chlorobenzenesulfonamido)hexyl]phenyl]butyric acid (12e) and 4-[4[1-(4- chlorobenzenesulfonamido)-5-methylhexyl]phenyl]butyric acid (12m) possessed good anti-LTD, activities. Compounds 12e and 12m were then evaluated for other related pharmacological effects involving the arachidonic acid cascade. These compounds appear to be hybrid eicosanoids antagonists having antagonistic activity against contraction of guinea-pig trachea induced by prostaglandin D2 (PGD2) and PGF(2α), as well as TXA2 and LTD4 antagonistic activities.

Synthesis and thoromboxane A2 antagonistic activity of [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives

Sakurai,Ogawa,Suzuki,Kato,Ohashi,Yasuda,Kato,Ito

, p. 765 - 777 (2007/10/03)

In order to find a new antiasthmatic and antithrombotic agents, various [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives were synthesized. Evaluation of these compounds for thromboxane A2 (TXA2) antag

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