162970-49-2 Usage
Description
2-Pyrrolidinone,3,3-difluoro-(9CI) is a chemical compound characterized by the molecular formula C4H6F2NO. It is a colorless liquid with a faint odor, known for its high solvency power and low toxicity, which makes it a versatile solvent in various industrial applications.
Uses
Used in Pharmaceutical Industry:
2-Pyrrolidinone,3,3-difluoro-(9CI) is used as a solvent for dissolving active pharmaceutical ingredients and other components in the manufacturing of medications. Its high solvency power allows for the efficient production of pharmaceutical formulations.
Used in Polymer Processing:
In the polymer industry, 2-Pyrrolidinone,3,3-difluoro-(9CI) serves as a solvent for dissolving polymers and additives during the production process. This helps in achieving desired properties and characteristics in the final polymer products.
Used in Electronics Manufacturing:
2-Pyrrolidinone,3,3-difluoro-(9CI) is utilized as a solvent in the electronics manufacturing industry for cleaning and degreasing electronic components, as well as for dissolving materials in the production of certain electronic devices.
Precautions:
While handling 2-Pyrrolidinone,3,3-difluoro-(9CI), it is important to exercise caution due to its potential to cause irritation to the skin and eyes. Prolonged exposure may also lead to adverse health effects. Therefore, proper safety precautions and adherence to regulations should be followed to minimize the risk of accidents or environmental damage.
Check Digit Verification of cas no
The CAS Registry Mumber 162970-49-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,9,7 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 162970-49:
(8*1)+(7*6)+(6*2)+(5*9)+(4*7)+(3*0)+(2*4)+(1*9)=152
152 % 10 = 2
So 162970-49-2 is a valid CAS Registry Number.
162970-49-2Relevant articles and documents
Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents
Humphries, Paul S.,Bersot, Ross,Kincaid, John,Mabery, Eric,McCluskie, Kerryn,Park, Timothy,Renner, Travis,Riegler, Erin,Steinfeld, Tod,Turtle, Eric D.,Wei, Zhi-Liang,Willis, Erik
supporting information, p. 293 - 297 (2018/01/04)
A series of novel carbazole-containing amides and ureas were synthesized. A structure–activity relationship study of these compounds led to the identification of potent cryptochrome modulators. Based on the desired pharmacokinetic/pharmacodynamic parameters and the results of efficacy studies in db/db mice, compound 50 was selected for further profiling.
An efficient synthesis of 3,3-difluoro-pyrrolidine hydrochloride starting with 2-chloro-2,2-difluoroacetic acid
Wei, Lulin,Makowski, Teresa M.,Rutherford, Jennifer L.
experimental part, p. 354 - 357 (2012/03/27)
A facile and fluorination-free synthesis of 3,3-difluoropyrrolidine hydrochloride (3), an important synthon in the synthesis of biologically active compounds, is reported. The seven-step synthesis starts from the commercially available 2-chloro-2,2-difluoroacetic acid (1) in a three-step telescoped process that produces crystalline N,N-diethyl-2,2-difluoro-3-hydroxy-4- nitrobutanamide (2). A convenient and high-yielding reductive nitromethylation of 2 followed by a catalytic hydrogenation/cyclization sequence and borane reduction affords 3 in good yield and purity.
