1629962-38-4Relevant academic research and scientific papers
Regio-, and stereoselective iodobromination of ynamides for synthesis of (E)-1-bromo-2-iodoenamides
Ide, Masataka,Yauchi, Yuta,Iwasawa, Tetsuo
, p. 3262 - 3267 (2014/06/09)
One-step synthesis of vicinal bromoiodoenamides from ynamides through IBr addition is described. Two types of IBr were used: commercially available IBr, and in situ generated IBr. This simple protocol enables highly efficient regio- and stereoselective iodobromination of the triple bond on a gram scale in anti-mode, and provides a potentially diverse scaffold for preparation of tetrasubstituted olefins. Copyright
