163071-53-2Relevant academic research and scientific papers
Synthetic and theoretical investigation on the one-pot halogenation of β-amino alcohols and nucleophilic ring opening of aziridinium ions
Chen, Yunwei,Sun, Xiang,Wu, Ningjie,Li, Jingbai,Jin, Shengnan,Zhong, Yongliang,Liu, Zirui,Rogachev, Andrey,Chong, Hyun-Soon
, p. 920 - 939 (2016/01/15)
Aziridinium ions are useful reactive intermediates for the synthesis of enantiomerically enriched building blocks. However, N,N-dialkyl aziridinium ions are relatively underutilized in the synthesis of optically active molecules as compared to other three
SYNTHESIS OF THERAPEUTIC AND DIAGNOSTIC DRUGS CENTERED ON REGIOSELECTIVE AND STEREOSELECTIVE RING OPENING OF AZIRIDINIUM IONS
-
Paragraph 0114; 0115, (2013/12/03)
Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.
Stereoselective synthesis of β-amino nitriles and 1,3-diamines
Reetz, Manfred T.,Kayser, Frank,Harms, Klaus
, p. 8769 - 8772 (2007/10/02)
Chiral β-N,N-dibenzylamino nitriles Bn2NCH(R)CH2CN, prepared in enantiomerically pure form from a-amino acids, can e deprotonated and stereoselectively alkylated to afford β-amino nitriles Bn2NCH(R)CH(R')CN with two stereo
