163130-99-2

Upstream product

• 163130-96-9 {(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-[3-(2,4-dinitro-phenyl)-3H-imidazol-4-yl]-ethyl}-carbamic acid tert-butyl ester 
• 163130-98-1 (S)-2-Amino-N-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-3-[3-(2,4-dinitro-phenyl)-3H-imidazol-4-yl]-propionamide 
• 104882-10-2 (2S,3R,4S)-2-[(tert-butyloxycarbonyl)amino]-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 122621-77-6 (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane 
• 163130-97-0 ((S)-1-{(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-[3-(2,4-dinitro-phenyl)-3H-imidazol-4-yl]-ethylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 163131-00-8 (S)-N-{(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-[3-(2,4-dinitro-phenyl)-3H-imidazol-4-yl]-ethyl}-2-(5-dimethylamino-naphthalene-1-sulfonylamino)-3-phenyl-propionamide 

Relevant academic research and scientific papers

Time-resolved ligand exchange reactions: Kinetic models for competitive inhibitors with recombinant human renin

The on and off rate constants (k(on) and k(off)) were determined for a series of peptidomimetic, competitive inhibitors of human renin using a novel binding assay. The method entails analyzing a pair of ligand exchange reactions in which a dansylated inhi