1632042-35-3Relevant academic research and scientific papers
A convergent and stereoselective total synthesis of phomolides G and H
Subba Reddy,Sivaramakrishna Reddy,Phaneendra Reddy,Yadav
, p. 501 - 504 (2014/03/21)
A stereoselective total synthesis of phomolides G and H, a polyketide natural products is described. The synthesis involves organocatalytic enantioselective asymmetric epoxidation, C1-Wittig olefination, and ring-closing metathesis as key steps. The use of organocatalytic MacMillan asymmetric epoxidation for the construction of two chiral centers of phomolides G and H makes this approach more attractive. Georg Thieme Verlag Stuttgart New York.
