163229-48-9

Basic information

• Product Name: 1-(TERT-BUTYL) 2-METHYL 1H-INDOLE-1,2-DICARBOXYLATE
• Synonyms: 1-(TERT-BUTYL) 2-METHYL 1H-INDOLE-1,2-DICARBOXYLATE;Methyl indole-2-carboxylate, N-BOC protected;1-(tert-Butyl)-2-methyl-1H-indole-1,2-dicarboxylate 97%;BOC-METHYL INDOLE-2-CARBOXYLATE;Methyl indole-2-carboxylate, N-BOC protected 97%;Methyl 1H-indole-2-carboxylate, N-BOC protected 97%;Methyl1H-indole-2-carboxylate,N-BOCprotected97%;TERT-BUTYL METHYL 1H-INDOLE-1,2-DICARBOXYLATE
• CAS NO: 163229-48-9
• Molecular Formula: C15H17NO4
• Molecular Weight: 275.3
• Mol File: 163229-48-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 66 °C
• Boiling Point: 387.3 °C at 760 mmHg
• Flash Point: 188 °C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 3.34E-06mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(TERT-BUTYL) 2-METHYL 1H-INDOLE-1,2-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(TERT-BUTYL) 2-METHYL 1H-INDOLE-1,2-DICARBOXYLATE(163229-48-9)
• EPA Substance Registry System: 1-(TERT-BUTYL) 2-METHYL 1H-INDOLE-1,2-DICARBOXYLATE(163229-48-9)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 163229-48-9(Hazardous Substances Data)

Usage

General Description

1-(tert-butyl) 2-methyl 1H-indole-1,2-dicarboxylate is a chemical compound with a molecular formula of C15H17NO4. It is a derivative of the indole-1,2-dicarboxylic acid, which is commonly used in the synthesis of pharmaceutical and organic compounds. This chemical is also known for its potential applications in the field of medicinal chemistry due to its biological activities. Its structure contains a tert-butyl group and a methyl group, and it is commonly used as a building block in the production of various drugs and related compounds. This chemical compound plays an important role in drug discovery and medicinal research due to its unique structure and potential therapeutic applications.

InChI:InChI=1/C15H17NO4/c1-15(2,3)20-14(18)16-11-8-6-5-7-10(11)9-12(16)13(17)19-4/h5-9H,1-4H3

Upstream product

• 136382-33-7 1-(tert-butoxycarbonyl)-1H-indole-2-carboxylic acid 
• 74-88-4 methyl iodide 
• 1477-50-5 Indole-2-carboxylic acid 
• 13732-33-7 ethyl α-(E-phenylhydrazono)propionate 
• 62-53-3 aniline 
• 101137-66-0 methyl2-<(E)-phenylhydrazono>propionate 
• 3770-50-1 2-carbethoxyindole 
• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 75400-67-8 indole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 144069-67-0 (S)-N-tert-butoxycarbonylindoline-2-carboxylic acid 
• 1005515-90-1 methyl N-(tert-butoxycarbonyl)-4,5,6,7-tetrahydroindole-2-carboxylate 
• 186704-03-0 methyl (+/-)-1-t-butoxycarbonyl-indoline-2-carboxylate 
• 1316178-05-8 (2R,3aR,7aR)-N-(benzyloxycarbonyl)-2-methyloctahydroindole-2-carboxylic acid 
• 1316178-01-4 (2S,3aS,7aS)-N-(benzyloxycarbonyl)-2-methyloctahydroindole-2-carboxylic acid 
• 1316177-99-7 methyl (2R,3aR,7aR)-N-(benzyloxycarbonyl)-2-methyloctahydroindole-2-carboxylate 
• 1316177-96-4 methyl (2S,3aS,7aS)-N-(benzyloxycarbonyl)-2-methyloctahydroindole-2-carboxylate 
• 1202-04-6 indole-2-carboxylic acid methyl ester 
• 123500-69-6 isopropyl 1H-indole-2-carboxylate 
• 1248796-70-4 C₁₇H₂₃NO₄ 

Relevant articles and documents

Enantioselective Borylative Dearomatization of Indoles through Copper(I) Catalysis

The enantioselective borylative dearomatization of a heteroaromatic compound has been achieved using a copper(I) catalyst and a diboron reagent. This reaction involves the regio- and enantioselective addition of active borylcopper(I) species to indole-2-carboxylates, followed by the diastereoselective protonation of the resulting copper(I) enolate to give the corresponding chiral indolines, which bear consecutive stereogenic centers.

Redox-Neutral Photocatalytic C?H Carboxylation of Arenes and Styrenes with CO2

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CAFFEINE INHIBITORS OF MTHFD2 AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.