163301-09-5

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 626-15-3 1,3-bis-(bromomethyl)benzene 

Downstream Products

• 565462-34-2 {4-[3-(4-hydroxymethyl-phenoxymethyl)-benzyloxy]-phenyl}-methanol 
• 390367-06-3 C₂₂H₂₀Br₂O₂ 
• 683248-56-8 C₃₆H₃₀O₆ 
• 565462-35-3 {4-[3-(4-mercaptomethyl-phenoxymethyl)-benzyloxy]-phenyl}-methanethiol 
• 1414888-91-7 C₃₆H₃₄N₂O₂ 
• 1414888-92-8 C₃₇H₃₃N₂O₂⁽¹⁺⁾*Cl^(1-) 
• 1414888-83-7 C₃₇H₃₂N₂O₂S 
• 1413282-65-1 C₂₆H₁₈O₄ 
• 1413282-60-6 C₂₆H₂₂O₄ 

Relevant academic research and scientific papers

Design and synthesis of novel chiral dihydroimidazolium cyclophanes as N-heterocyclic carbene precatalysts

A series of novel diphenyl ethylenediamine (DPEN) derived C2 symmetric dihydroimidazolium cyclophanes were designed and synthesized as organo NHC precatalysts. The resultant organo NHC-catalyzed reactions with superior enantioselectivity than t

Designed compounds for recognition of 10 base Pairs of DNA with two at binding sites

Short AT base pair sequences that are separated by a small number of GCs are common in eukaryotic parasite genomes. Cell-permeable compounds that bind effectively and selectively to such sequences present an attractive therapeutic approach. Compounds with

Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors

Known PTP1B inhibitors with bis-anionic moieties exhibit potent inhibitory activity, good selectivity, however, they are incapable of penetrating cellular membranes. Based upon our finding of a new pharmacophoric group in inhibition of PTP1B and the struc

Multicomponent synthesis of new bis(pyranopyrazoles) and their antimicrobial–antioxidant evaluations

One-pot, three-component reactions were utilized to obtain a series of new symmetrical bis(pyranopyrazoles) built around six rigid linkers in good yields and in the short durations under normal conditions. The structures of the prepared compounds were confirmed using their IR, 1H-NMR, 13C-NMR and ESI-MS spectral parameters. The bis(pyranopyrazoles) 3b and 3f exhibited significant antimicrobial action against Klebsiella pneumoniae, Fusarium oxysporum and Penicillium glabrum at a minimum inhibitory concentration (MIC) value of 3.12 μg mL-1, which is equivalent to the MIC of the standard drug. trans-Butene-linked bis(pyranopyrazole) 3f was also associated with a good radical scavenging activity similar to that of ascorbic acid (a standard antioxidant).

Novel PTP1B enzyme inhibitor, preparation method and applications thereof

The present invention provides a novel PTP1B enzyme inhibitor, a preparation method and applications thereof, and particularly discloses a class of bis 2-substituted ethylene sulfonate compounds and a preparation method thereof, and uses of the bis 2-substituted ethylene sulfonate compounds as the PTP1B enzyme activity inhibitor. According to the present invention, the prepared novel compound has good PTP1B enzyme activity inhibition effect, and has the application value in preparation of drugs for treatment and prevention of diabetes and obesity.

Design and synthesis of novel chiral dihydroimidazolium cyclophanes as N-heterocyclic carbene precatalysts

A series of novel diphenyl ethylenediamine (DPEN) derived C2 symmetric dihydroimidazolium cyclophanes were designed and synthesized as organo NHC precatalysts. The resultant organo NHC-catalyzed reactions with superior enantioselectivity than t

Four-step route to novel bisflavylium dications - First synthesis of phloroglucinol-type derivatives

Various bisflavylium dications have been prepared in an efficient four-step manner utilizing the acid-mediated condensation between bis(arylethynylketones) and activated phenols as the key step. Of special note is that phloroglucinol-type bisflavylium sal

Synthesis and characterization of new organic phosphonates monomers as flame retardant additives for polymers

Commercially available polyphenols react with diethylphosphite to give polyphosphonates, which are easily transformed by LDA in good yields to polyorthohydroxy aryl phosphonates. Moreover, some bis-benzyl aminobenzyl phosphonates have been prepared in good yields. These new monomers are of great relevance for the synthesis of thermal resistant polycondensates containing phosphonate moieties.

Tether-directed selective synthesis of fulleropyrrolidine bisadducts

Selective synthesis of C60 bisadducts has been achieved by using the Prato 1,3-dipolar cycloaddition of tethered bis-azomethine ylides. New bis(benzaldehydes) 1-4 tethered by a rigid linker were prepared and used to direct the second cycloaddit