163333-52-6

Upstream product

• 79145-92-9 N-((tert-butoxy)carbonyl)-4-(bis(2-chloroethyl)amino)-L-phenylalanine 
• 163333-56-0 2,3-bis(palmitoylamino)propan-1-ol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 148-82-3 L-PAM 
• 192223-81-7 2,3-Bis-hexadecanoylamino-propionic acid methyl ester 

Relevant academic research and scientific papers

The synthesis of novel melphalan derivatives as potential antineoplastic agents

Five derivatives of melphalan (S)-4-[bis(2-chloroethyl)amino]phenylalanine), an alkylating agent presently employed as an antieoplastic in humans, were designed and synthesised as potential prodrugs. Their antitumour activity was tested against P388 leuka

p-[Bis(2-chloroethyl)amino]phenylalanine compounds

Antileukemic compounds of formula (I): STR1 in which: R1 represents hydrogen, linear or branched (C1 -C6)-alkoxycarbonyl or substituted or unsubstituted phenylalkoxycarbonyl, R2 represents any one of the followi