79145-92-9

Basic information

• Product Name: BOC-4-BIS(2-CHLOROETHYL)AMINO-L-PHENYLALANINE
• Synonyms: BOC-4-BIS(2-CHLOROETHYL)AMINO-L-PHENYLALANINE
• CAS NO: 79145-92-9
• Molecular Formula: C₁₈H₂₆Cl₂N₂O₄
• Molecular Weight: 405.32
• Mol File: 79145-92-9.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BOC-4-BIS(2-CHLOROETHYL)AMINO-L-PHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-4-BIS(2-CHLOROETHYL)AMINO-L-PHENYLALANINE(79145-92-9)
• EPA Substance Registry System: BOC-4-BIS(2-CHLOROETHYL)AMINO-L-PHENYLALANINE(79145-92-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 79145-92-9(Hazardous Substances Data)

Upstream product

• 148-82-3 L-PAM 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 34619-03-9 tert-butyldicarbonate 
• 3223-07-2 melphalan hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 

Downstream Products

• 316147-12-3 1-({N-(tert-butyloxycarbonyl)-4-[bis(2-chloroethyl)amino]-L-phenylalanyl}-amino)-3-(dimethylamino)propane 
• 769135-97-9 2-hydroxy-7-methoxy-5-methyl-naphthalene-1-carboxylic acid 2-(3-{4-[bis-(2-chloroethyl)amino]phenyl}-2-tert-butoxycarbonylamino-propionyloxy)ethyl ester 
• 844879-82-9 4-[bis(2-chloroethyl)butyloxycarbonyl]-L-phenylalanyl-L-proline benzyl ester 
• 163333-52-6 2,3-Bis(palmitoylamino)-(O)-{(S)-N-tert-butoxycarbonyl-4-[bis(2-chloroethyl)amino]phenylalanyl}propan-1-ol 

Relevant articles and documents

Derivatives of nitrogen mustard anticancer agents with improved cytotoxicity

In previous studies, we demonstrated that esters of bendamustine containing a basic moiety are far more cytotoxic anticancer agents than their parent compound and that the substitution of the labile ester moiety by a branched ester or an amide markedly in

Design and synthesis of chromone-nitrogen mustard derivatives and evaluation of anti-breast cancer activity

Chromone has emerged as one of the most important synthetic scaffolds for antitumor activity, which promotes the development of candidate drugs with better activity. In this study, a series of nitrogen mustard derivatives of chromone were designed and syn

Bifunctional cytotoxin and application thereof

The invention provides a bifunctional cytotoxin containing a duocarmycin analogue and a nitrogen mustard compound, and further provides an antibody drug conjugate coupled with the bifunctional cytotoxin and pharmaceutical application of the antibody drug