163395-24-2 Usage
Uses
Used in Pharmaceutical Research:
3-Fluoro-4-Nitrophenylacetic Acid is used as a key intermediate in the synthesis of pharmaceutical compounds for various therapeutic applications. Its unique structure allows for the development of new drugs with novel mechanisms of action and improved pharmacological properties.
Used in Chemical Research:
In the field of chemical research, 3-Fluoro-4-Nitrophenylacetic Acid is utilized as a building block for the synthesis of a wide range of organic compounds. Its presence of a nitro group and a fluorine atom on the phenyl ring provides opportunities for further chemical modifications and the creation of new chemical entities with potential applications in various industries.
Used in Drug Development:
3-Fluoro-4-Nitrophenylacetic Acid is employed as a starting material in the development of new drugs. Its unique structural features make it a valuable component in the design and synthesis of innovative pharmaceutical agents with improved efficacy, selectivity, and safety profiles.
Used in Material Science:
Due to its notable chemical structure, 3-Fluoro-4-Nitrophenylacetic Acid may also find applications in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity, which can be utilized in various industrial processes.
Check Digit Verification of cas no
The CAS Registry Mumber 163395-24-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,3,9 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 163395-24:
(8*1)+(7*6)+(6*3)+(5*3)+(4*9)+(3*5)+(2*2)+(1*4)=142
142 % 10 = 2
So 163395-24-2 is a valid CAS Registry Number.
163395-24-2Relevant academic research and scientific papers
QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS
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Page/Page column 99, (2014/12/09)
Compounds of formula (Ι') that are Fibroblast Growth Factor Inhibitors (FGFR) and are therefore useful for the treatment of diseases treatable by inhibition of FGFR are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
A Convergent Synthesis of 14-Membered F-O-G Ring Analogs of the Teicoplanin Binding Pocket via Intramolecular SNAr Reaction
Zhu, Jieping,Beugelmans, Rene,Bourdet, Sebastien,Chastanet, Jacqueline,Roussi, George
, p. 6389 - 6396 (2007/10/03)
An intramolecular SNAr reaction for efficient macrocyclization via biaryl ether formation was developed for syntheses of the 14-membered macrocycles 2 and 3 related to F-O-G ring of teicoplanin 1.Chloride as well as fluoride could be used as the leaving group in this reaction.However, the latter was prefered since it required milder conditions.Both ortho and para nitro, fluoro disubstituted aromatic rings were suitable for the macrocyclization reaction with tethered aryl oxides.The nonproteinogenic α-amino acid 23, required for the synthesis of 3, was prepared via an asymmetric Strecker synthesis using (R)-phenylglycinol as a chiral auxiliary.The overall synthetic strategy was convergent, and the cyclization could be performed in the presence of the highly sensitive arylglycine unit without racemization.
