64123-77-9

Basic information

• Product Name: METHYL 3-FLUOROPHENYLACETATE
• Synonyms: METHYL 3-FLUOROPHENYLACETATE;Methyl 3-fluorophenylacetate,98%;Methyl 2-(3-fluorophenyl)acetate;(3-Fluorophenyl)acetic acid methyl ester;2-(3-Fluorophenyl)acetic acid methyl ester;3-Fluorobenzeneacetic acid methyl ester;Methyl 2-(3-fluorophenyl);Methyl 3-fluorophenylacetate, 97.5%
• CAS NO: 64123-77-9
• Molecular Formula: C₉H₉FO₂
• Molecular Weight: 168.16
• Mol File: 64123-77-9.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 204.0±15.0℃ (760 Torr)
• Flash Point: 75.3±15.3℃
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 1.148±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.27mmHg at 25°C
• Refractive Index: 1.487-1.489
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 3-FLUOROPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-FLUOROPHENYLACETATE(64123-77-9)
• EPA Substance Registry System: METHYL 3-FLUOROPHENYLACETATE(64123-77-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 64123-77-9(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to slightly yellow liquid

InChI:InChI=1/C9H9FO2/c1-12-9(11)6-7-3-2-4-8(10)5-7/h2-5H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 326-62-5 2-fluorophenyl acetonitrile 
• 331-25-9 (3-fluorophenyl)acetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 124-41-4 sodium methylate 
• 118112-20-2 5-Fluoro-bicyclo[4.2.0]octa-1,3,5-trien-7-one 
• 865-34-9 lithium methanolate 

Downstream Products

• 169339-41-7 methyl 2-(3-fluoro-4-nitrophenyl)acetate 
• 52059-53-7 2-(3-fluorophenyl)ethanol 
• 1011528-25-8 methyl α-(m-fluorophenyl)-α-diazoacetate 
• 619323-20-5 methyl 2-(3-fluorophenyl)pent-4-enoate 
• 29640-99-1 methyl 2-(5-fluoro-2-nitrophenyl)acetate 

Relevant articles and documents

PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST

Disclosed herein is a pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as A2A receptor antagonist, and a pharmaceutical composition comprising the same. Also disclosed herein is a method of treating cancer using the pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof as A2A receptor antagonist.

Pyrimidine onium compound and application thereof

The invention relates to a pyrimidine onium compound, nitride oxides, salt of the nitride oxides and a composition comprising the compound. The invention further relates to an application of the compound to plant pest control.

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers

With the aim to discover a gastric antisecretory agent more potent than the existing proton pump inhibitors, novel 3,4-dihydro-1H-spiro(naphthalene-2,2′-piperidin)-1-one derivatives, which could occupy two important lipophilic pockets (described as LP-1 and LP-2) of H+,K+-ATPase and can strongly bind to the K+-binding site, were designed based on a docking model. Among the compounds synthesized, compound 4d showed a strong H+,K+-ATPase-inhibitory activity and a high stomach concentration in rats, resulting in potent inhibitory action on histamine-stimulated gastric acid secretion in rats. Furthermore, 4d exerted significant inhibitory action on histamine-stimulated gastric-acid secretion in rats with a rapid onset and moderate duration of action after the administration. These findings may lead to a new insight into the drug design of potassium-competitive acid blockers.