163399-75-5Relevant academic research and scientific papers
Synergistic Pd/Amine-Catalyzed Stereodivergent Hydroalkylation of 1,3-Dienes with Aldehydes: Reaction Development, Mechanism, and Stereochemical Origins
Wang, Hongfa,Zhang, Qinglong,Zhang, Ruiyuan,Zi, Weiwei
supporting information, p. 10948 - 10962 (2021/08/03)
Metal-hydride-catalyzed hydroalkylation of 1,3-dienes with enolizable carbonyl compounds is an atom- and step-economical method for preparing chiral molecules with allylic stereocenters. Although high diastereo- and enantioselectivities have been achieved
Determination of the absolute configurations and total synthesis of new immunosuppressants, mycestericins E and G
Fujita, Tetsuro,Hamamichi, Norimitsu,Matsuzaki, Tohru,Kitao, Yuki,Kiuchi, Masatoshi,Node, Manabu,Hirose, Ryoji
, p. 8599 - 8602 (2007/10/02)
The absolute configurations of two new immunosuppressant, mycestericins E (1) and G (2), were established and both compounds were synthesized starting from 1,8-octanediol and a fully protected methyl (2S,4R)-oxazolidine-4-carboxylate 3. Compounds 5 and 22
Asymmetric Total Synthesis of ISP-I (Myriocin, Thermozymocidin), a Potent Immunosuppressive Principle in the Isaria sinclairii Metabolite
Shigeki, Sano,Kobayashi, Yoshimaro,Kondo, Tatsuya,Takebayashi, Maki,Maruyama, Shigeki,et al.
, p. 2097 - 2100 (2007/10/02)
Asymmetric total synthesis of ISP-I has been achived by utilizing highly selectrive E-olefin formation based on the Schlosser-modified Wittig reaction and highly diastereoselective aldol reactions employing both chiral heterocyclic derivatives, 3-acetyl-(4S)-isopropyl-1,3-thiazolidine-2-thione and ethyl -2-yl carboxylate.
