16340-48-0

Usage

Uses

Used in Organic Synthesis:
2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline is used as a key intermediate in organic synthesis for the creation of various chemical compounds. Its unique structure allows for the formation of new chemical entities through reactions such as substitution, addition, and condensation.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline is utilized as a starting material for the development of new drugs. Its potential applications include the synthesis of novel therapeutic agents that could address unmet medical needs.
Used in Drug Development:
2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline is employed as a building block in the development of new drugs, where its molecular structure can be modified to create compounds with specific biological activities. This makes it a valuable component in the design and synthesis of innovative pharmaceuticals.
Used in Material Science:
Beyond its applications in organic synthesis and pharmaceuticals, 2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline also has potential uses in material science. Its unique properties may contribute to the development of new materials with specialized characteristics for various applications.

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 694-83-7 rac-diaminocyclohexane 
• 34126-95-9 2-aminocyclohexanecarboxamide 
• 64162-07-8 2-amino-cyclohexanecarboxylic acid ethyl ester 
• 20439-47-8 (1R,2R)-1,2-diaminocyclohexane 
• 134-81-6 benzil 
• 21436-03-3 (S,S)-1,2-diaminocyclohexane 
• 1121-22-8 trans-1,2-Diaminocyclohexane 
• 50-00-0 formaldehyd 
• 501-65-5 diphenyl acetylene 

Relevant academic research and scientific papers

YbCl3-catalyzed one-pot synthesis of dihydropyrazines, piperazines, and pyrazines

A simple and efficient synthetic approach to dihydropyrazines via YbCl 3-catalyzed reaction of α-hydroxyketones with diamines under mild conditions was developed. The corresponding 2,3-subsitituted piperazines and pyrazines were obtained through tandem conversion of dihydropyrazines with good yields.

Efficient synthesis of quinoxalines with hypervalent iodine as a catalyst

Various biologically important quinoxalines were efficiently synthesized in excellent yields via one-pot reaction between 1,2-diaminobenzenes and internal alkynes. The method utilizes inexpensive and readily available hypervalent iodine source, such as (diacetoxyiodo)benzene (PhI(OAc)2) and proved to be a better alternative as compared to expensive transition metal catalysts. Quinoxaline 4i [(2-phenyl-3-(3,4,5-trimethoxy phenyl)quinoxaline)] was evaluated for leukemia cancer cell lines and turned out to be a good candidate.

FeCl3 and morpholine as efficient cocatalysts for the one-step synthesis of quinoxalines from α-hydroxyketones and 1,2-diamines

One-step conversion including intramolecular hydrogen bond decomposition, aerobic oxidation, and condensation from α-hydroxyketones and 1,2-diamines into quinoxalines is reported using FeCl3 and morpholine as cocatalysts. Taylor & Francis Group, LLC.

A new approach to enantiomerically pure bis-imidazoles derived from trans-1,2-diaminocyclohexane

Racemic as well as enantiomerically pure trans-1,1′-(cyclohexane-1,2-diyl)bis(imidazole N-oxides) were prepared from trans-cyclohexane-1,2-bis(methylidenamine) and 1,2-dione monooximes (α-hydroxyiminoketones). The enantiomeric purity of selected products was determined by means of 1H NMR spectroscopy in the presence of (+)-(R)-(tert-butyl)(phenyl)phosphonothioic acid as a chiral solvating agent. Deoxygenation by treatment with Raney-nickel led to the corresponding chiral bis-imidazoles.

ORGANOMETALLIC COMPLEX, AND LIGHT-EMITTING DEVICE AND ELECTRONIC APPLIANCE USING THE SAME

In a general formula (1), each of R1 and R2 represents any one of hydrogen, an alkyl group, a halogen group, -CF3, an alkoxy group, and an aryl group. M represents an element that belongs to Group 9 or Group 10. Here, an alkyl group

SINTESIS, ESTUDIO DINAMICO POR RMN Y CALCULOS TEORICOS DE HEXAHIDRO- Y TETRAHIDROQUINOXALINAS 2,3-DISUSTITUIDAS

The synthesis of 2,3-disubstituted hexahydroquinoxaline stereoisomers from 1,2-diaminocyclohexanes and the corresponding α-dicarbonylic derivatives and their oxidation to tetrahydroquinoxalines is described.Their 1H- and 13C-NMR spectra are analyzed and a