163430-53-3

Upstream product

• 50790-28-8 methyl 4-(methanesulfonylamino)benzoate 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 852475-44-6 methyl 4-[(4-cyano-4-ethoxycarbonylbutyl)methanesulfonylamino]benzoate 
• 852475-46-8 methyl 4-[[3-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)propyl]methanesulfonylamino]benzoate 
• 852475-48-0 4-[[3-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)propyl]methanesulfonylamino]benzoic acid 
• 852475-50-4 di-tert-butyl N-{4-[[3-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)propyl]methanesulfonylamino]benzoyl}-L-glutamate 

Relevant academic research and scientific papers

Radical isomerization via intramolecular ipso substitution of N-arylamides: Aryl translocation from nitrogen to carbon

N-Aryl-N-(3-bromopropyl)amides are converted to N-(3-arylpropyl)amides under standard radical generating conditions via intramolecular ipso attack of the alky radicals which generates spiro cyclohexadienyl radical intermediates.

Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway

The synthesis and evaluation of 10-methanesulfonyl-DDACTHF (1), 10-methanesulfonyl-5-DACTHF (2), and 10-methylthio-DDACTHF (3) as potential inhibitors of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide ribonucleotide t